- ►annals.org [PDF] M Dahl, A Tybjaerg-Hansen, P Lange, J … - Annals of internal medicine, 2002 - Am Coll Physicians Change in Lung Function and Morbidity from Chronic Obstructive ... Pulmonary
Disease in 1 -Antitrypsin MZ Heterozygotes: A Longitudinal ... Morten Dahl, MD;
Anne Tybjærg-Hansen, MD, DMSc; Peter Lange, MD, DMSc; Jørgen Vestbo, MD, ... Cited by 73 - Related articles - All 5 versions
GE Silva, DL Sherrill, S Guerra, RA Barbee - Chest, 2003 - chestjournal.chestpubs.org Background: It is well-known that the homozygous deficiency of α 1
-antitrypsin, phenotype PiZZ, is associated with an increased risk of COPD.
However, studies evaluating the association between the heterozygous forms ... Cited by 26 - Related articles - BL Direct - All 5 versions
N Seersholm, A Kok-Jensen - Respiratory medicine, 1998 - Elsevier The index cases and the non-index cases were similar with respect to sex, age
and follow-up time, but differed in smoking habits and FEV 1 . Among the smokers
there was no significant difference in pack-years between index cases and ... Cited by 30 - Related articles - BL Direct - All 5 versions
- Free from Publisher AJ Sandford, TD Weir, JJ Spinelli, PD Pare - American journal of respiratory cell and molecular …, 1999 - ncbi.nlm.nih.gov 1: Am J Respir Cell Mol Biol. 1999 Feb;20(2):287-91. Z and S mutations of the
alpha1-antitrypsin gene and the risk of chronic obstructive pulmonary disease. ... Cited by 57 - Related articles - BL Direct - All 3 versions
- ►bmj.com CP Hersh, M Dahl, NP Ly, CS Berkey, BG … - British Medical Journal, 2004 - thorax.bmj.com Results: In 16 studies that reported COPD as a categorical outcome, the combined
odds ratio (OR) for PI MZ versus PI MM (normal genotype) was 2.31 (95% CI 1.60
to 3.35). The summary OR was higher in case-control studies (OR 2.97; 95% ... Cited by 58 - Related articles - BL Direct - All 10 versions
GM Turino, AF Barker, ML Brantly, AB Cohen, … - American journal of respiratory and critical care …, 1996 - 171.66.122.149 This report describes the clinical characteristics of a group of 59 individuals
with the PI*SZ phenotype and alpha 1-antitrypsin (alpha 1- AT) deficiency,
identified during recruitment of a registry for subjects with severe alpha ... Cited by 107 - Related articles - BL Direct - All 4 versions
- ►chestpubs.org FJ de Serres - Chest, 2002 - chestjournal.chestpubs.org Study design: Genetic epidemiologic studies in the peer-reviewed literature have
been used in an exploratory study to estimate the number of carriers and the
number of those individuals who are homozygous or heterozygous for the two ... Cited by 173 - Related articles - BL Direct - All 8 versions
- ►171.66.122.149 N SEERSHOLM, JONTR WILCKE, A KOK- … - American journal of respiratory and critical care …, 2000 - 171.66.122.149 Whether subjects heterozygous for 1 -antitrypsin ( 1 -AT) deficiency are at risk
for development of obstructive pulmonary disease (OPD) has been discussed for
the past three decades. Both cohort and case-control studies have reached ... Cited by 49 - Related articles - BL Direct - All 4 versions
- ►ersj.org.uk M Luisetti, M Miravitlles, RA Stockley - European Respiratory Journal, 2002 - ersj.org.uk A commitment of the Alpha One International Registry members, belonging to 15
national registries, is to meet every 2 yrs in an open scientific conference to
provide a scientific and clinical update on the deficiency. The second ... Cited by 23 - Related articles - BL Direct - All 6 versions
