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Scholar Results 1 - 10 of about 101 related to Sundararajan: Survival associated with 5-fluorouracil-based adjuvant chemotherapy among elderly.... (0.11 sec) 

Survival associated with 5-fluorouracil-based adjuvant chemotherapy among elderly patients …

- annals.org [PDF] 
V Sundararajan, N Mitra, JS Jacobson, VR … - Annals of internal medicine, 2002 - Am Coll Physicians
Background: Randomized clinical trials have demonstrated the efficacy of
adjuvant 5-fluorouracil (5-FU)–based chemotherapy af- ter surgical resection
of node-positive colon cancer. Although this treatment became the standard ...
Cited by 107 - Related articles - BL Direct - All 6 versions

Effectiveness of adjuvant fluorouracil in clinical practice: a population-based cohort study of …

- ascopubs.org
TJ Iwashyna, EB Lamont - Journal of Clinical Oncology, 2002 - jco.ascopubs.org
PURPOSE: Although randomized controlled trials (RCTs) consistently show that
adjuvant fluorouracil (5-FU) extends the survival of patients with stage III
colon cancer, it is not yet known whether this benefit exists in ...
Cited by 84 - Related articles - BL Direct - All 7 versions

Variations in the use of adjuvant chemotherapy for node-positive colon cancer in the elderly …


V Sundararajan, VR Grann, JS Jacobson, H … - Cancer journal (Sudbury, Mass.) - ncbi.nlm.nih.gov
BACKGROUND: Since 1990, the recommended adjuvant therapy for patients with
surgically resected node-positive colon cancer has been 5-fluorouracil (5-FU),
usually in combination with leucovorin or levamisole. The purpose of this ...
Cited by 58 - Related articles - BL Direct

Age and adjuvant chemotherapy use after surgery for stage III colon cancer

- oxfordjournals.org
D Schrag, LD Cramer, PB Bach, CB Begg - JNCI Journal of the National Cancer Institute, 2001 - jnci.oxfordjournals.org
Background: Randomized trials have established that 5-fluorouracil-based
adjuvant chemotherapy following resection of stage III colon cancer reduces
subsequent mortality by as much as 30%. However, the extent to which ...
Cited by 206 - Related articles - BL Direct - All 9 versions

Use of adjuvant chemotherapy and radiation therapy for rectal cancer among the elderly: a …

- ascopubs.org
AI Neugut, AT Fleischauer, V Sundararajan, N … - Journal of Clinical Oncology, 2002 - jco.ascopubs.org
PATIENTS AND METHODS: The linked Surveillance, Epidemiology, and
End-Results–Medicare database was used to identify 1,807 Medicare
beneficiaries 65 years of age with stage II or III rectal cancer who ...
Cited by 84 - Related articles - BL Direct - All 7 versions

A pooled analysis of adjuvant chemotherapy for resected colon cancer in elderly patients


DJ Sargent, RM Goldberg, SD Jacobson, JS … - New England Journal of Medicine, 2001 - content.nejm.org
Methods We performed a pooled analysis, based on the intention to treat, of
individual patient data from seven phase 3 randomized trials (involving 3351
patients) in which the effects of postoperative fluorouracil plus ...
Cited by 374 - Related articles - BL Direct - All 8 versions

Adjuvant chemotherapy for stage III colon cancer: implications of race/ethnicity, age, and …


JM Jessup, A Stewart, FL Greene, BD Minsky - Jama, 2005 - Am Med Assoc
You are seeing this message because your Web browser does not support basic Web
standards. Find out more about why this message is appearing and what you can do
to make your experience on this site better. ... Context A 1990 National ...
Cited by 77 - Related articles - BL Direct - All 5 versions

Duration of adjuvant chemotherapy for colon cancer and survival among the elderly

- ascopubs.org
AI Neugut, M Matasar, X Wang, R McBride, … - Journal of Clinical Oncology, 2006 - jco.ascopubs.org
Purpose In randomized trials, patients with stage III colon cancer who received
6 months of fluorouracil (FU)-based adjuvant chemotherapy had better survival
than patients who did not. However, little is known about the predictors ...
Cited by 35 - Related articles - All 7 versions

Adjuvant or palliative chemotherapy for colorectal cancer in patients 70 years or older

- ascopubs.org
RA Popescu, A Norman, PJ Ross, B Parikh, … - Journal of Clinical Oncology, 1999 - jco.ascopubs.org
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From the Gastrointestinal Unit, Royal Marsden Hospital, London, and Sutton, ...
Cited by 163 - Related articles - BL Direct - All 7 versions

Completion of therapy by Medicare patients with stage III colon cancer


SA Dobie, LM Baldwin, JA Dominitz, B … - JNCI Journal of the National Cancer Institute, 2006 - jnci.oxfordjournals.org
Background: Certain factors, such as race or age, are known to be associated
with variation in initiation of adjuvant chemotherapy for stage III colon
cancer, but little is known about what factors are associated with ...
Cited by 36 - Related articles - BL Direct - All 8 versions


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