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Scholar Results 1 - 10 of about 101 related to Ghofrani: Combination therapy with oral sildenafil and inhaled iloprost for severe pulmonary.... (0.10 sec) 

Combination therapy with oral sildenafil and inhaled iloprost for severe pulmonary …

- annals.org [PDF] 
HA Ghofrani, R Wiedemann, F Rose, H … - Annals of internal medicine, 2002 - Am Coll Physicians
Patients: 30 patients with severe pulmonary arterial hypertension (n 16),
chronic thromboembolic pulmonary hypertension (n 13), or pulmonary hypertension
due to aplasia of the left pulmo- nary artery (n 1), all classified as New ...
Cited by 424 - Related articles - BL Direct - All 14 versions

Effect of inhaled iloprost plus oral sildenafil in patients with primary pulmonary hypertension

- ahajournals.org
H Wilkens, A Guth, J Konig, N Forestier, B … - Circulation, 2001 - Am Heart Assoc
Methods and Results— The short-term effects of 8.4 to 10.5 µg of aerosolized
iloprost, the phosphodiesterase type 5 inhibitor sildenafil, and the combination
thereof were compared in 5 patients with primary pulmonary hypertension. ...
Cited by 364 - Related articles - BL Direct - All 11 versions

Oral sildenafil is an effective and specific pulmonary vasodilator in patients with pulmonary …

- ahajournals.org
E Michelakis, W Tymchak, D Lien, L Webster, … - Circulation, 2002 - Am Heart Assoc
Methods and Results— We studied 13 consecutive patients (mean±SEM, 44±2
years of age; 9 women) referred for consideration of heart-lung transplantation
or as a guide to medical therapy. All but one were functional class III or ...
Cited by 429 - Related articles - BL Direct - All 13 versions

Oral sildenafil as long-term adjunct therapy to inhaled iloprost in severe pulmonary arterial …

- onlinejacc.org
HA Ghofrani, F Rose, RT Schermuly, H … - Journal of the American College of Cardiology, 2003 - Elsevier
We sought to investigate the impact of adjunct sildenafil on exercise capacity
and hemodynamic parameters in patients with pulmonary arterial hypertension
(PAH) who fulfilled predefined criteria of deterioration despite ongoing ...
Cited by 264 - Related articles - BL Direct - All 15 versions

Sildenafil for treatment of lung fibrosis and pulmonary hypertension: a randomised controlled …


HA Ghofrani, R Wiedemann, F Rose, RT … - The Lancet, 2002 - Elsevier
Pulmonary vascular resistance index was reduced by nitric oxide (−21·9%, 95%
Cl −14·1 to −36·2), epoprostenol (−36·9%, −24·4 to −59·6), and
sildenafil (−32·5%, −10·2 to −54·1). However, ratio of pulmonary ...
Cited by 436 - Related articles - All 7 versions

Inhaled iloprost for severe pulmonary hypertension


H Olschewski, G Simonneau, N Galie, T … - New England Journal of Medicine, 2002 - content.nejm.org
Methods We compared repeated daily inhalations of 2.5 or 5.0 µg of iloprost
(six or nine times per day; median inhaled dose, 30 µg per day) with inhalation
of placebo. A total of 203 patients with selected forms of severe pulmonary ...
Cited by 845 - Related articles - BL Direct - All 19 versions

Sildenafil for long-term treatment of nonoperable chronic thromboembolic pulmonary …

- atsjournals.org
HA Ghofrani, RT Schermuly, F Rose, R … - American journal of respiratory and critical care …, 2003 - Am Thoracic Soc
Only a small percentage of patients with chronic thromboembolic pulmonary
hypertension are eligible for pulmonary thrombendarterectomy. We investigated
the effects of oral sildenafil on hemodynamics and exercise capacity in 12 ...
Cited by 215 - Related articles - BL Direct - All 6 versions

Effect of sildenafil on the acute pulmonary vasodilator response to inhaled nitric oxide in …


JJ Lepore, A Maroo, NL Pereira, LC Ginns, … - The American journal of cardiology, 2002 - Elsevier
Breathing low concentrations of nitric oxide (NO) produces selective pulmonary
vasodilatation and increases exercise capacity in patients with pulmonary
hypertension of various etiologies,[1 and 2] and an acute pulmonary ...
Cited by 147 - Related articles - All 5 versions

Continuous subcutaneous infusion of treprostinil, a prostacyclin analogue, in patients with …

- 171.66.122.149
G Simonneau, RJ Barst, N Galie, R Naeije, S … - American journal of respiratory and critical care …, 2002 - 171.66.122.149
Pulmonary arterial hypertension is a life-threatening disease for which
continuous intravenous prostacyclin has proven to be effective. However, this
treatment requires a permanent central venous catheter with the associated ...
Cited by 629 - Related articles - BL Direct - All 9 versions

Combination therapy with bosentan and sildenafil in idiopathic pulmonary arterial …

- ersjournals.com
MM Hoeper, C Faulenbach, H Golpon, J … - European Respiratory Journal, 2004 - Eur Respiratory Soc
The 6MWD at baseline was 346±66 m and improved to 403±80 m 3 months after
introduction of bosentan treatment. However, this effect was not sustained and,
after an interval of 11±5 months, the walk distance had declined to ...
Cited by 167 - Related articles - BL Direct - All 8 versions


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