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Scholar Results 1 - 10 of about 101 related to Molldrem: Antithymocyte globulin for treatment of the bone marrow failure associated with.... (0.09 sec) 

Antithymocyte globulin for treatment of the bone marrow failure associated with …

- annals.org
JJ Molldrem, E Leifer, E Bahceci, Y … - Annals of internal medicine, 2002 - Am Coll Physicians
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Background: Almost half of the deaths that result from myelodysplastic ...
Cited by 133 - Related articles - BL Direct - All 4 versions

A pilot study of antithymocyte globulin (ATG) in the treatment of patients with'low-risk' …


SB Killick, G Mufti, JD Cavenagh, A Mijovic … - British journal of haematology, 2003 - pt.wkhealth.com
Sally B. Killick, 1 Ghulam Mufti, 2 Jamie D. Cavenagh, 3 Alex Mijovic, 2 Janet
L. Peacock, 4 ... Edward C. Gordon-Smith, 1 David T. Bowen 5 and Judith CW
Marsh 1 1Department of Haematology, ... St George's Hospital, 2Department ...
Cited by 76 - Related articles - BL Direct - All 6 versions

A simple method to predict response to immunosuppressive therapy in patients with …

- bloodjournal.org
Y Saunthararajah, R Nakamura, R Wesley, QJ … - Blood, 2003 - Am Soc Hematology
Immunosuppression with antithymocyte globulin (ATG) or cyclosporine (CSA) can be
used to treat the cytopenia associated with myelodysplastic syndrome (MDS).
Previously, we identified HLA-DR15, younger age, and shorter duration of ...
Cited by 80 - Related articles - BL Direct - All 5 versions

HLA-DR15 (DR2) is overrepresented in myelodysplastic syndrome and aplastic anemia and …

- hematologylibrary.org
Y Saunthararajah, R Nakamura, JM Nam, J … - Blood, 2002 - bloodjournal.hematologylibrary.org
Myelodysplastic syndrome (MDS) is a clonal hematopoietic disorder characterized
by bone marrow failure, marrow dysplasia, and a tendency to evolve to acute
leukemia. There is accumulating evidence that T-cell-mediated immune ...
Cited by 135 - Related articles - BL Direct - All 4 versions

Antithymocyte globulin has limited efficacy and substantial toxicity in unselected anemic …

- bloodjournal.org [PDF] 
DP Steensma, A Dispenzieri, SB Moore, G … - Blood, 2003 - Am Soc Hematology
The myelodysplastic syndrome (MDS) includes a heterogeneous group of marrow
disorders characterized by ineffective hematopoi- esis and a variable risk of
leukemic transformation. Because most patients with MDS are diagnosed after ...
Cited by 55 - Related articles - All 6 versions

Antithymocyte globulin (ATG)-based therapy in patients with myelodysplastic syndromes


S Yazji, FJ Giles, AM Tsimberidou, EH Estey, … - Leukemia, 2003 - nature.com
The purpose of this study was to determine the efficacy of and tolerance to
antithymocyte globulin (ATG)-based therapy in patients with myelodysplastic
syndrome (MDS). Therapy consisted of ATG 40 mg/kg/day daily intravenously ...
Cited by 37 - Related articles - BL Direct - All 3 versions

A prospective, randomised, phase II study of horse antithymocyte globulin vs rabbit …


M Stadler, U Germing, KO Kliche, KM Josten, … - Leukemia, 2004 - nature.com
Immunosuppression has recently been proposed for low-risk myelodysplastic
syndromes (MDS) to reverse bone marrow failure by inhibiting intramedullary
secretion of proapoptotic cytokines. We treated 35 MDS patients (24 ...
Cited by 52 - Related articles - All 3 versions

Loss of T-lymphocyte clonal dominance in patients with myelodysplastic syndrome …

- hematologylibrary.org
JN Kochenderfer, S Kobayashi, ED Wieder, C … - Blood, 2002 - bloodjournal.hematologylibrary.org
To investigate whether dominant T-cell clones are present in patients with MDS,
we studied 12 patients with cytopenia who were enrolled in a randomized clinical
trial of ATG, ATG plus fludarabine, or ATG plus cyclosporine. We ...
Cited by 71 - Related articles - BL Direct - All 5 versions

Cyclosporin A therapy in hypoplastic MDS patients and certain refractory anaemias without …


A JonÁšovÁ, R NeuwirtovÁ, J CermAk, V … - Br J Haematol, 1998 - interscience.wiley.com
We report 17 cytopenic patients with myelodysplastic syndrome (MDS) of
refractory anaemia (RA) subtype with hyper-, normo- or hypo-cellular bone marrow
(BM), who were treated with cyclosporin A (CyA). Substantial haematological ...
Cited by 199 - Related articles - BL Direct - All 4 versions

Antithymocyte globulin for patients with myelodysplastic syndrome


JJ Molldrem, M Caples, D Mavroudis, M Plante … - British Journal of Haematology, 1997 - interscience.wiley.com
Twenty-five transfusion-dependent myelodysplastic syndrome (MDS) patients (with
< 20% blasts) were treated in a phase II study with antithymocyte globulin (ATG)
at 40 mg/kg/d for four doses and then followed with blood counts every 2 ...
Cited by 217 - Related articles - BL Direct - All 4 versions


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