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Linezolid: the first oxazolidinone antimicrobial

- annals.org [PDF] 
RC Moellering Jr - Annals of internal medicine, 2003 - Am Coll Physicians
TO THE EDITOR: In his review of linezolid, Moellering (1) appro- priately calls
for clinical trials comparing the efficacy and safety of linezolid with those of
other new drugs active against resistant gram- positive organisms, ...
Cited by 202 - Related articles - BL Direct - All 7 versions

Linezolid: The First Oxazolidinone Antimicrobial


SOF ACTIVITY - Annals of Internal Medicine, 2003 - Am Coll Physicians
Linezolid is the first of a new class of antimicrobial agents, the
oxazolidinones, to be approved for clinical use in the United States and
elsewhere. The drug is a totally synthetic compound, which lessens the ...
Related articles

Linezolid for the treatment of multidrug-resistant, gram-positive infections: experience …


MC Birmingham, CR Rayner, AK Meagher, SM … - Clinical Infectious Diseases, 2003 - UChicago Press
Featured in New York Times "Searching the Web for Flu Outbreaks" November 28,
2008 Using Internet Searches for Influenza Surveillance Philip M. Polgreen,
Yiling Chen, David M. Pennock, and Forrest D. Nelson One study, published ...
Cited by 201 - Related articles - BL Direct - All 6 versions

Worldwide assessment of linezolid's clinical safety and tolerability: comparator-controlled …

- nih.gov
E Rubinstein, R Isturiz, HC Standiford, LG … - Antimicrobial agents and chemotherapy, 2003 - Am Soc Microbiol
Linezolid, an oxazolidinone antibiotic, has 100% oral bioavailability and
favorable activities against gram-positive pathogens including
multidrug-resistant staphylococci, enterococci, and pneumococci. Safety ...
Cited by 74 - Related articles - BL Direct - All 11 versions

Hematologic effects of linezolid: summary of clinical experience


SL Gerson, SL Kaplan, JB Bruss, V Le, FM … - Antimicrobial Agents and Chemotherapy, 2002 - pubmedcentral.nih.gov
Myelosuppression is associated with antibiotics (2-4, 6, 7, 9, 10, 12, 13).
Similarly, linezolid, which is effective against gram-positive bacteria (5, 16,
17-19, 21), has been associated with reversible myelosuppression (11, 14; ...
Cited by 139 - Related articles - BL Direct - All 9 versions

Pharmacokinetics of linezolid in subjects with renal dysfunction

- nih.gov
ME Brier, DJ Stalker, GR Aronoff, DH Batts, … - Antimicrobial agents and chemotherapy, 2003 - Am Soc Microbiol
Linezolid is a member of a new, unique class of synthetic antibacterial agents
called oxazolidinones that are effective against gram-positive bacteria,
including vancomycin-resistant organisms. We tested the hypothesis that the ...
Cited by 53 - Related articles - BL Direct - All 10 versions

Linezolid versus vancomycin in treatment of complicated skin and soft tissue infections

- nih.gov
J Weigelt, K Itani, D Stevens, W Lau, M … - Antimicrobial Agents and Chemotherapy, 2005 - Am Soc Microbiol
Skin and soft tissue infections (SSTIs) are a common cause of morbidity in both
the community and the hospital. An SSTI is classified as complicated if the
infection has spread to the deeper soft tissues, if surgical intervention ...
Cited by 191 - Related articles - BL Direct - All 11 versions

A review of linezolid: the first oxazolidinone antibiotic


DL Stevens, B Dotter, K Madaras-Kelly - Expert Review of Anti-Infective Therapy, 2004 - ingentaconnect.com
© Future Drugs Ltd. All rights reserved. ISSN 1478-7210 ... C ONTENTS
Chemistry Mechanism of action Antimicrobial spectrum Pharmacology
Pharmacokinetics Adverse reactions Drug & food interactions Clinical ...
Cited by 33 - Related articles - All 4 versions

Quinupristin-dalfopristin and linezolid: evidence and opinion


GM Eliopoulos, LD Saravolatz - Clinical infectious diseases, 2003 - UChicago Press
Featured in New York Times "Searching the Web for Flu Outbreaks" November 28,
2008 Using Internet Searches for Influenza Surveillance Philip M. Polgreen,
Yiling Chen, David M. Pennock, and Forrest D. Nelson One study, published ...
Cited by 142 - Related articles - BL Direct - All 8 versions

Antimicrobial resistance to linezolid


VG Meka, HS Gold, GM Eliopoulos - Clinical Infectious Diseases, 2004 - UChicago Press
Featured in New York Times "Searching the Web for Flu Outbreaks" November 28,
2008 Using Internet Searches for Influenza Surveillance Philip M. Polgreen,
Yiling Chen, David M. Pennock, and Forrest D. Nelson One study, published ...
Cited by 93 - Related articles - BL Direct - All 5 versions


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