- ►annals.org IK Srivastava, MA Liu - Annals of internal medicine, 2003 - Am Coll Physicians Gene vaccines are a new approach to immunization and immunotherapy in which,
rather than a live or inactivated organism (or a subunit thereof), one or more
genes that encode proteins of the pathogen are delivered. The goal of this ... Cited by 99 - Related articles - BL Direct - All 6 versions
IK Srivastava, M Singh - International Journal of Pharmaceutical Medicine, 2005 - ingentaconnect.com Abstract Compared with conventional approaches, DNA vaccine technology is a
relatively new methodology for producing effective vaccines and has the major
advantage of being simple and not requiring any special tech- niques for ... Cited by 1 - Related articles - BL Direct - All 4 versions
MA Liu - Vaccines. Preventing Disease and Protecting Health, 2003 - ingentaconnect.com The DNA vaccines are simple rings of DNA containing a gene encoding an antigen,
and a promoter/terminator to make the gene express in mammalian cells. They are
a prom- ising new approach for generating all types of desired immunity— ... Cited by 162 - Related articles - BL Direct - All 9 versions
- ►scielo.br JJ Donnelly, JB Ulmer, JW Shiver, MA Liu - Annual review of immunology, 1997 - Annual Reviews ▪ Abstract Observations in the early 1990s that plasmid DNA could directly
transfect animal cells in vivo sparked exploration of the use of DNA plasmids to
induce immune responses by direct injection into animals of DNA encoding ... Cited by 1186 - Related articles - BL Direct - All 35 versions
A Margaret - Vaccines: preventing disease & protecting health, 2004 - books.google.com DMA VACCINES: A REVIEW Margaret A. L/ INTRODUCTION The DNA vaccines are simple
rings of DNA containing a gene encoding an antigen, and a promoter/terminator to
make the gene express in mammalian cells. They are a prom- ising new ... Related articles
RG Whalen - Emerg. Infect. Dis, 1996 - cdc.gov A novel and powerful method for vaccine research, colloquially known as DNA
vaccines, involves the deliberate introduction into tissues of a DNA plasmid
carrying an antigen-coding gene that transfects cells in vivo and results ... Cited by 53 - Related articles - Cached - All 7 versions
TP Le, KM Coonan, RC Hedstrom, Y … - Vaccine, 2000 - Elsevier DNA-based vaccines are considered to be potentially revolutionary due to their
ease of production, low cost, long shelf life, lack of requirement for a cold
chain and ability to induce good T-cell responses. Twenty healthy adult ... Cited by 172 - Related articles - BL Direct - All 9 versions
- ►nih.gov S Zucchelli, S Capone, E Fattori, A Folgori, … - Journal of Virology, 2000 - Am Soc Microbiol We describe an improved genetic immunization strategy for eliciting a full
spectrum of anti-hepatitis C virus (HCV) envelope 2 (E2) glycoprotein responses
in mammals through electrical gene transfer (EGT) of plasmid DNA into ... Cited by 92 - Related articles - BL Direct - All 5 versions
J Donnelly, K Berry, JB Ulmer - International journal for parasitology, 2003 - Elsevier DNA vaccines have been widely used in laboratory animals and non-human primates
over the last decade to induce antibody and cellular immune responses. This
approach has shown some promise, in models of infectious diseases of both ... Cited by 86 - Related articles - All 4 versions
RM Conry, DT Curiel, TV Strong, SE Moore, … - Clinical cancer research, 2002 - AACR Despite an abundance of preclinical data, relatively little is known regarding
the efficacy of DNA vaccination in humans. Here, we present results from a
dose-escalation clinical trial of a dual expression plasmid encoding ... Cited by 103 - Related articles - BL Direct - All 5 versions