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Scholar Results 1 - 10 of about 101 related to Chung: The hereditary nonpolyposis colorectal cancer syndrome: genetics and clinical implications. (0.10 sec) 

The hereditary nonpolyposis colorectal cancer syndrome: genetics and clinical implications

- annals.org [PDF] 
DC Chung, AK Rustgi - Annals of internal medicine, 2003 - Am Coll Physicians
Basic studies of DNA replication and repair have provided surpris- ing and
pivotal insights into a novel pathway of tumorigenesis. Defects in the DNA
mismatch repair process dramatically increase the risk for specific types ...
Cited by 182 - Related articles - BL Direct - All 5 versions

AGA technical review on hereditary colorectal cancer and genetic testing.


FM Giardiello, JD Brensinger, GM Petersen - Gastroenterology, 2001 - ncbi.nlm.nih.gov
This literature review and the recommendations therein were prepared for the
American Gastroenterological Association (AGA) Clinical Practice and Practice
Economics Committee. The paper was approved by the Committee on March 20, ...
Cited by 231 - Related articles - BL Direct - All 2 versions

Molecular analysis of hereditary nonpolyposis colorectal cancer in the United States: high …

- nih.gov
A Wagner, A Barrows, JT Wijnen, H van der … - The American Journal of Human Genetics, 2003 - Elsevier
The identification of germline mutations in families with HNPCC is hampered by
genetic heterogeneity and clinical variability. In previous studies, MSH2 and
MLH1 mutations were found in approximately two-thirds of the ...
Cited by 140 - Related articles - BL Direct - All 9 versions

Evaluation of microsatellite instability and immunohistochemistry for the prediction of …

- aacrjournals.org
SS Wahlberg, J Schmeits, G Thomas, M Loda, … - Cancer research, 2002 - AACR
Forty-eight hereditary nonpolyposis colorectal carcinoma (HNPCC) familiesfor
which a tumor sample was available were evaluated for the presence of germ-line
mutations in MSH2 and MLH1, tumor microsatellite instability (MSI), and ...
Cited by 133 - Related articles - BL Direct - All 4 versions

遗传性结直肠癌发病的分子基础诊断及其临床防治


容哲, 卢嘉, 薄建华, 张诗武 - 武警医学院学报, 2005 - cqvip.com
首页; 期刊导航; 知识社区; 学者空间; 学术机构; 专题导读;
充值中心; 论文翻译. 登录 注册 帮助. 维普资讯 ...
Cited by 1 - Related articles - All 6 versions

[PDF] A National Cancer Institute workshop on hereditary nonpolyposis colorectal cancer …


MA Rodriguez-Bigas, CR Boland, SR Hamilton … - Journal of the National Cancer Institute, 1997 - jnci.oxfordjournals.org
Hereditary nonpolyposis colorectal cancer (HNPCC) is a dis- tinct autosomal
dominant syndrome accounting for approxi- mately 5%–6% of the total colorectal
cancer burden with clinical and pathologic features caused by defective ...
Cited by 684 - Related articles - BL Direct - All 6 versions

Revised Bethesda Guidelines for hereditary nonpolyposis colorectal cancer (Lynch syndrome) …

- oxfordjournals.org
A Umar, CR Boland, JP Terdiman, S Syngal, A … - JNCI Journal of the National Cancer Institute, 2004 - jnci.oxfordjournals.org
Affiliations of authors: Division of Cancer Prevention (AU, ETH, SS), Center for
Cancer Research (JCB), Division of Cancer Control and Population Sciences (ANF),
National Cancer Institute, National Institutes of Health, Department of ...
Cited by 715 - Related articles - BL Direct - All 9 versions

Population-based molecular detection of hereditary nonpolyposis colorectal cancer

- ascopubs.org [PDF] 
R Salovaara, A Loukola, P Kristo, H … - Journal of Clinical Oncology, 2000 - jco.ascopubs.org
Purpose: Cancer morbidity and mortality can be dramatically reduced by
colonoscopic screening of in- dividuals with the hereditary nonpolyposis
colorectal cancer (HNPCC) syndrome, creating a need to identify HNPCC. We ...
Cited by 313 - Related articles - BL Direct - All 10 versions

The colon cancer burden of genetically defined hereditary nonpolyposis colon cancer


WS Samowitz, K Curtin, HH Lin, MA Robertson, … - Gastroenterology, 2001 - medscape.com
Journal Scan is the clinician's guide to the latest clinical research findings
in Gastroenterology, Hepatology, Gastrointestinal Endoscopy, and The New England
Journal of Medicine. Short summaries of feature articles include links to ...
Cited by 178 - Related articles - BL Direct - All 8 versions

Impact of microsatellite testing and mismatch repair protein expression on the clinical …


R Ward, C Meldrum, R Williams, E Mokany, R … - Journal of cancer research and clinical oncology, 2002 - Springer
Abstract Purpose: Identification of germline mutations in mismatch repair genes
is increasingly being used to guide clinical practice in hereditary
non-polyposis colon cancer. The aim of this study was to retrospectively ...
Cited by 16 - Related articles - BL Direct - All 5 versions


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