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Scholar Results 1 - 10 of about 101 related to Pichler: Delayed drug hypersensitivity reactions. (0.11 sec) 

Delayed drug hypersensitivity reactions

- annals.org [PDF] 
WJ Pichler - Annals of internal medicine, 2003 - Am Coll Physicians
D rug-induced adverse reactions are a major health problem (1–3). Most adverse
effects, so-called type A reactions, are due to the pharmacologic action of a
drug. Idiosyncratic and immune-mediated side effects, which are not ...
Cited by 190 - Related articles - BL Direct - All 5 versions

Delayed Drug Hypersensitivity Reactions


HOWDOTCR DRUGS - Annals of Internal Medicine, 2003 - Am Coll Physicians
Drug-induced adverse reactions are a major health problem (1–3). Most adverse
effects, so-called type A reactions, are due to the pharmacologic action of a
drug. Idiosyncratic and immune-mediated side effects, which are not ...
Related articles

T cell involvement in cutaneous drug eruptions


Y Hari, K Frutig-Schnyder, M Hurni, N … - Clinical & Experimental Allergy, 2001 - interscience.wiley.com
It is also possible that your web browser is not configured or not able to
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degraded, the site should continue to be functional. We recommend using the ...
Cited by 93 - Related articles - BL Direct - All 4 versions

The lymphocyte transformation test in the diagnosis of drug hypersensitivity


WJ Pichler, J Tilch - Allergy, 2004 - interscience.wiley.com
Diagnosis of drug hypersensitivity is difficult, as an enormous amount of
different drugs can elicit various immune-mediated diseases with distinct
pathomechanism. The lymphocyte transformation test (LTT) measures the ...
Cited by 136 - Related articles - BL Direct - All 4 versions

Immune mechanism of drug hypersensitivity* 1


WJ Pichler - Immunology and allergy clinics of North America, 2004 - Elsevier
Drug-induced adverse reactions are common and normally classified as type A
reactions, owing to the pharmacologic action of the drug, or type B reactions,
which comprise idiosyncratic and immune-mediated side effects that are not ...
Cited by 29 - Related articles - BL Direct - All 4 versions

Hypersensitivity reactions to carbamazepine: characterization of the specificity, phenotype, …

- aspetjournals.org
DJ Naisbitt, M Britschgi, G Wong, J Farrell, … - Molecular pharmacology, 2003 - ASPET
Administration of carbamazepine (CBZ) causes hypersensitivity reactions
clinically characterized by skin involvement, eosinophilia, and systemic
symptoms. These reactions have an immune etiology; however, the role of T ...
Cited by 84 - Related articles - BL Direct - All 3 versions

Characterization of drug-specific T cells in lamotrigine hypersensitivity


DJ Naisbitt, J Farrell, G Wong, JH Depta, … - The Journal of Allergy and Clinical Immunology, 2003 - Elsevier
Background: Lamotrigine is associated with hypersensitivity reactions, which are
most commonly characterized by skin rash. An immune etiology has been
postulated, though the nature of this is unclear. Objectives: The aim of ...
Cited by 88 - Related articles - All 8 versions

Pharmacological interaction of drugs with antigen-specific immune receptors: the pi concept


WJ Pichler - Current opinion in allergy and clinical immunology, 2002 - journals.lww.com
Recent findings: Drugs were stimulatory for T-cells if they bound covalently to
peptides or proteins, but also if the drug had structural features allowing it
to bind in a labile way (noncovalently) to the major histocompatibility ...
Cited by 82 - Related articles - All 4 versions

[PDF] Diagnosis of nonimmediate reactions to b-lactam antibiotics


A Romano, M Blanca, MJ Torres, A Bircher, W … - Allergy, 2004 - eaaci.net
Nonimmediate manifestations (ie occurring more than 1 h after drug admin-
istration), particularly maculopapular and urticarial eruptions, are common
during b-lactam treatment. The mechanisms involved in most nonimmediate ...
Cited by 85 - Related articles - View as HTML - BL Direct - All 6 versions

Immunological principles of adverse drug reactions: the initiation and propagation of …


DJ Naisbitt, S Gordon, M Pirmohamed, B Park - Drug safety, 2000 - ingentaconnect.com
Abstract . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
. . . . . . . . . . . . . . . 483 1. Clinical Classification of Drug
Hypersensitivity . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ...
Cited by 79 - Related articles - BL Direct - All 7 versions


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