- ►annals.org [PDF] M Hummel, E Bonifacio, S Schmid, M Walter, A … - Annals of internal medicine, 2004 - Am Coll Physicians Brief Communication: Early Appearance of Islet Autoantibodies ... Predicts
Childhood Type 1 Diabetes in Offspring of Diabetic Parents ... Michael Hummel,
MD; Ezio Bonifacio, PhD; Sandra Schmid, PhD; Markus Walter, MD; Annette ... Cited by 39 - Related articles - BL Direct - All 4 versions
- ►nih.gov P Achenbach, K Koczwara, A Knopff, H Naserke … - Journal of Clinical Investigation, 2004 - Am Soc Clin Investig Children at risk for type 1 diabetes can develop early insulin autoantibodies
(IAAs). Many, but not all, of these children subsequently develop multiple islet
autoantibodies and diabetes. To determine whether disease progression is ... Cited by 66 - Related articles - BL Direct - All 10 versions
P Achenbach, K Warncke, J Reiter, HE Naserke … - Diabetes, 2004 - Am Diabetes Assoc Family history of type 1 diabetes and autoantibodies to the islet antigens
insulin (IAA), glutamate decarboxylase (GADA), and the protein tyrosine
phosphatase-like protein IA-2 (IA-2A) are strong predictors of type 1 ... Cited by 90 - Related articles - BL Direct - All 6 versions
- ►endojournals.org T Kimpimaki, P Kulmala, K Savola, A Kupila, S … - Journal of Clinical Endocrinology & Metabolism, 2002 - Endocrine Soc The aim of this study was to evaluate the frequency and predictive value of
diabetes-associated autoantibodies, such as islet cell antibodies (ICA) and
autoantibodies to insulin (IAA), GAD65 (GADA), and the IA-2 molecule ... Cited by 71 - Related articles - BL Direct - All 5 versions
M Walter, E Albert, M Conrad, E Keller, M … - Diabetologia, 2003 - Springer Aim/hypothesis. Type 1 diabetes (T1D) is an autoim- mune disease with multiple
susceptibility genes. The aim of this study was to determine whether combining
IDDM1/HLA and IDDM2/insulin (INS) 5′ variable number of tandem repeat ... Cited by 41 - Related articles - BL Direct - All 3 versions
PG Colman, C Steele, JJ Couper, SJ Beresford … - Diabetologia, 2000 - Springer Type I (insulin-dependent) diabetes mellitus is caused by immune-mediated
destruction of the insu- lin-secreting beta cells in the islets of the pancreas
[1]. Studies in first-degree relatives of patients with Type I diabetes ... Cited by 50 - Related articles - BL Direct - All 3 versions
- ►endojournals.org HE Naserke, E Bonifacio, AG Ziegler - Journal of Clinical Endocrinology & Metabolism, 1999 - Endocrine Soc Insulin autoantibodies (IAA) are early sensitive markers of prediabetes in the
young. The aim of this study was to assess whether, using IgG-specific
measurement with a protein A/G assay, IAA are already present at birth, and ... Cited by 40 - Related articles - BL Direct - All 4 versions
JM LaGasse, MS Brantley, NJ Leech, RE … - Diabetes Care, 2002 - Am Diabetes Assoc RESULTS—Six subjects developed diabetes (median interval 2.8 years), all from
among the 12 individuals with multiple d-aab, representing 50% positive
predictive value (95% CI 25–75%) and 100% sensitivity (58–100%). Among ... Cited by 76 - Related articles - BL Direct - All 5 versions
- ►endojournals.org JM Barker, KJ Barriga, L Yu, D Miao, HA … - Journal of Clinical Endocrinology & Metabolism, 2004 - Endocrine Soc Diabetes Autoimmunity Study in the Young (DAISY) has followed 1972 children for
islet autoimmunity and diabetes: 837 first-degree relatives of persons with type
1 diabetes and 1135 general population newborns identified through human ... Cited by 101 - Related articles - BL Direct - All 6 versions
- ►diabetesjournals.org P Achenbach, E Bonifacio, K Koczwara, AG … - Diabetes, 2005 - Am Diabetes Assoc The natural history of autoimmune type 1 diabetes in children is associated with
the appearance of islet autoantibodies early in life, which is influenced by
genetic and environmental factors. Once islet autoantibodies have ... Cited by 37 - Related articles - BL Direct - All 9 versions
