- ►annals.org [PDF] SK Vesely, JJ Perdue, MA Rizvi, DR Terrell, … - Annals of internal medicine, 2004 - Am Coll Physicians Background: Treatment of chronic refractory idiopathic throm- bocytopenic
purpura is a dilemma because many patients have minimal symptoms, response to
treatment is uncertain, and treat- ments may have serious adverse effects. ... Cited by 79 - Related articles - All 7 versions
- ►hematologylibrary.org K Kojouri, SK Vesely, DR Terrell, JN George - Blood, 2004 - bloodjournal.hematologylibrary.org Splenectomy was the primary treatment for idiopathic (immune) thrombocytopenic
purpura (ITP) prior to the introduction of glucocorticoids more than 50 years
ago. 1 For the past 50 years, splenectomy has remained a standard treatment ... Cited by 145 - Related articles - BL Direct - All 9 versions
D Sources, D Extraction, D Synthesis - Ann Intern Med, 2004 - moon.ouhsc.edu Background: Treatment of chronic refractory idiopathic throm- bocytopenic
purpura is a dilemma because many patients have minimal symptoms, response to
treatment is uncertain, and treat- ments may have serious adverse effects. ... Related articles - View as HTML - All 4 versions
F Maloisel, E Andrès, J Zimmer, E Noel, A … - The American journal of medicine, 2004 - Elsevier Adults with chronic idiopathic thrombocytopenic purpura (ITP) in whom
standard-dose corticosteroids and splenectomy have failed or who have
contraindications to these therapies often require further treatment for ... Cited by 50 - Related articles - All 9 versions
DB Cines, JB Bussel - Blood, 2005 - bloodjournal.hematologylibrary.org Until recently, experience from numerous centers over more than a half-century
indicated that the typical adult with ITP is a woman, generally between 18 and
40 years of age. 6 Gender disparity largely disappears among the elderly. ... Cited by 115 - Related articles - BL Direct - All 9 versions
- ►annals.org [PDF] DM Arnold, F Dentali, MA Crowther, RM Meyer … - Annals of internal medicine, 2007 - Am Coll Physicians Background: Rituximab, a monoclonal anti-CD20 antibody, is in- creasingly used
to treat idiopathic thrombocytopenic purpura (ITP). ... Purpose: To
systematically review the literature on the efficacy and safety of ... Cited by 137 - Related articles - BL Direct - All 3 versions
E Bourgeois, MT Caulier, C Delarozee, M … - British journal of haematology, 2003 - interscience.wiley.com Summary. Splenectomy remains the most effective treatment of chronic autoimmune
idiopathic thrombocytopenia (ITP) (ie of > 6 months duration). Treatment of
patients refractory to splenectomy (with absence of response or relapse ... Cited by 45 - Related articles - BL Direct - All 6 versions
JN George, GE Raskob, SK Vesely, D Moore, … - American journal of hematology, 2003 - cancercaresouthtexas.com We conducted a randomized clinical trial in adults with a new diagnosis of ITP
and a platelet count <30,000/mL to test the hypothesis that initial intermittent
treatment with anti-D may avoid or defer the need for splenectomy when ... Cited by 30 - Related articles - View as HTML - BL Direct - All 4 versions
R McMillan, C Durette - Blood, 2004 - bloodjournal.hematologylibrary.org Adult chronic immune thrombocytopenic purpura (ITP) is an autoimmune disorder
manifested by thrombocytopenia from the effects of antiplatelet autoantibodies
and T lymphocyte–mediated platelet cytotoxicity. Multiple studies show ... Cited by 53 - Related articles - BL Direct - All 9 versions
JN George - Journal of Thrombosis and Haemostasis, 2006 - w3.ouhsc.edu Summary. In immune thrombocytopenic purpura (ITP), thrombocytopenia is a result
of both increased platelet destruction and insufficient platelet production. In
adults, the course is commonly chronic, but most patients never experience ... Cited by 65 - Related articles - View as HTML - BL Direct - All 6 versions