- ►annals.org [PDF] C Bellanne-Chantelot, D Chauveau, JF Gautier, … - Annals of internal medicine, 2004 - Am Coll Physicians Setting: 2 departments of diabetes, 1 department of internal medicine, and 1
department of nephrology. Participants: 8 probands with diabetes diagnosed
before 40 years of age and nondiabetic kidney disease who were selected ... Cited by 103 - Related articles - BL Direct - All 5 versions
- ►nih.gov EL Edghill, C Bingham, S Ellard, AT … - British Medical Journal, 2006 - jmg.bmj.com Results: Twenty three different heterozygous HNF-1ß mutations were identified
in 23/160 subjects (14%), including 10 novel mutations (V61G, V110G, S148L,
K156E, Q176X, R276Q, S281fsinsC, R295P, H324fsdelCA, Q470X). Seven (30%) ... Cited by 77 - Related articles - BL Direct - All 10 versions
C Bingham, S Ellard, TRP Cole, KE Jones, LIS … - Kidney international, 2002 - nature.com Renal tract malformations are, on occasion, associated with uterine
malformations. The transcription factor hepatocyte nuclear factor (HNF)-1 is
expressed from the earliest stages of development of the Wolffian duct, the ... Cited by 70 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org C Bellanné-Chantelot, S Clauin, D Chauveau, … - Diabetes, 2005 - Am Diabetes Assoc Maturity-onset diabetes of the young (MODY) 5 is caused by mutations in the TCF2
gene encoding the transcription factor hepatocyte nuclear factor-1β. However,
in 60% of the patients with a phenotype suggesting MODY5, no point mutation ... Cited by 59 - Related articles - BL Direct - All 4 versions
- ►pnas.org C Haumaitre, E Barbacci, M Jenny, MO Ott, G … - Proceedings of the National Academy of Sciences, 2005 - National Acad Sciences Heterozygous mutations in the human POU-homeobox TCF2 (vHNF1, HNF1β) gene are
associated with maturity-onset diabetes of the young, type 5, and abnormal
urogenital tract development. Recently, pancreas atrophies have been ... Cited by 58 - Related articles - All 9 versions
- Free from Publisher ER Pearson, MK Badman, CR Lockwood, PM … - Diabetes Care, 2004 - Am Diabetes Assoc OBJECTIVE—Mutations in the highly homologous transcription factors hepatocyte
nuclear factor (HNF)-1α and -1β cause maturity-onset diabetes of the young
types 3 and 5, respectively. Diabetes due to HNF-1α mutations is well ... Cited by 33 - Related articles - BL Direct - All 6 versions
- ►oxfordjournals.org C Bingham, AT Hattersley - Nephrology Dialysis Transplantation, 2004 - ERA-EDTA Mutations in the gene encoding the transcription factor hepatocyte nuclear
factor (HNF)-1ß have recently been described in association with a variety of
abnormalities of renal development. The most consistent clinical feature is ... Cited by 42 - Related articles - BL Direct - All 4 versions
C Bingham, S Ellard, L Allen, M Bulman, M … - Kidney international, 2000 - nature.com The transcription factor hepatocyte nuclear factor (HNF)-1 functions as a
homodimer or as a heterodimer with the structurally related protein HNF-1 . Both
are expressed sequentially in rat kidney development, with HNF-1 being ... Cited by 111 - Related articles - BL Direct - All 4 versions
- ►asnjournals.org T Ulinski, S Lescure, S Beaufils, V Guigonis … - Journal of the American Society of Nephrology, 2006 - Am Soc Nephrol The hepatocyte nuclear factor-1 encoded by the TCF2 gene plays a role for the
specific regulation of gene expression in various tissues such as liver, kidney,
intestine, and pancreatic islets and is involved in the embryonic ... Cited by 46 - Related articles - BL Direct - All 5 versions
TH Lindner, PR Njolstad, Y Horikawa, L Bostad … - Human Molecular Genetics, 1999 - Oxford Univ Press Mutations in the homeodomain-containing transcription factor hepatocyte nuclear
factor (HNF)-1[beta] are the cause of one form of maturity-onset diabetes of the
young (MODY), type 5 (MODY5). We have studied a Norwegian family, N5, with ... Cited by 155 - Related articles - BL Direct - All 8 versions
