R Chou, M Helfand - Annals of internal medicine, 2005 - Am Coll Physicians An evidence synthesis of a medical intervention should assess the balance of benefits and
harms. Investigators performing systematic reviews of harms face challenges in finding data,
rating the quality of harms reporting, and synthesizing and displaying data from different ... Cited by 45 - Related articles - All 4 versions
PL Santaguida, M Helfand, P Raina - Annals of internal medicine, 2005 - Am Coll Physicians Increasingly, consumers, clinicians, regulatory bodies, and insurers are using systematic reviews
of drug interventions to select treatments and set policies. Although a systematic review cannot
provide all the information a clinician needs to make an informed choice for therapy, it can ... Cited by 15 - Related articles - All 4 versions
S Golder, Y Loke, HM McIntosh - BMC Medical Research …, 2006 - biomedcentral.com In order to determine where methodological research is most needed to improve systematic reviews
of adverse effects of health care interventions, we conducted a descriptive analysis of systematic
reviews published between 1994 and 2005. We searched the Database of Abstracts of ... Cited by 17 - Related articles - Cached - All 9 versions
- ►annals.org A Tatsioni, DA Zarin, N Aronson, DJ … - Annals of internal …, 2005 - Am Coll Physicians Diagnostic tests are critical components of effective health care. They help determine treatments
that are most beneficial for a given patient. Their assessment is a complex process that includes
such challenges as a dearth of studies that evaluate clinical outcomes and lack of data on ... Cited by 80 - Related articles - All 4 versions
SL Norris, D Atkins - Annals of internal medicine, 2005 - Am Coll Physicians Randomized, controlled trials (RCTs) are firmly established as the standard for determining which
medical treatments are effective. In some areas of health care, however, among them
surgery, public health, and the organization of health care delivery, most evidence ... Cited by 51 - Related articles - All 5 versions
- ►annals.org D Atkins, K Fink, J Slutsky - Annals of internal medicine, 2005 - Am Coll Physicians To provide decision makers with the best available evidence, the Agency for Healthcare Research
and Quality established a network of Evidence-based Practice Centers across North
America. The centers perform systematic reviews on important questions posed by ... Cited by 27 - Related articles - All 4 versions
HM McIntosh, NF Woolacott, AM … - BMC Medical Research …, 2004 - biomedcentral.com One review question focused on providing information on specific harmful effects to furnish an
economic model, the other two addressed much broader questions. All three reviews included
randomised and observational data, although each defined the inclusion criteria ... Cited by 19 - Related articles - Cached - All 10 versions
S Derry, K Loke, JK Aronson - BMC Medical Research Methodology, 2001 - biomedcentral.com We would expect information on adverse drug reactions in randomised clinical trials to be easily
retrievable from specific searches of electronic databases. However, complete retrieval of such
information may not be straightforward, for two reasons. First, not all clinical drug trials ... Cited by 60 - Related articles - Cached - All 9 versions
S Wieland, K Dickersin - Journal of clinical epidemiology, 2005 - Elsevier We compared the results of a series of Medline searches to a gold standard comprising 58 reports
from a 1996 systematic review examining the relationship between oral contraceptives and the
development of breast cancer. Sensitivity (the proportion of gold standard publications ... Cited by 12 - Related articles - All 15 versions
- ►annals.org L Hartling, FA McAlister, BH Rowe, J … - Annals of internal …, 2005 - Am Coll Physicians The authors discuss 3 challenges in conducting and interpreting any systematic review that are
particularly relevant for systematic reviews of therapeutic devices or surgical procedures: 1) inclusion
or exclusion of grey literature, 2) the role of nonrandomized studies, and 3) issues in ... Cited by 34 - Related articles - All 4 versions
