- ►annals.org [PDF] NG Mahon, RT Murphy, CA MacRae, ALP … - Annals of internal medicine, 2005 - Am Coll Physicians Background: Idiopathic dilated cardiomyopathy is often familial, and apparently
healthy relatives may have latent, early, or un- diagnosed established disease.
Objective: To determine the prevalence and natural history of asymptomatic ... Cited by 35 - Related articles - BL Direct - All 7 versions
J Schönberger, L Kühler, E Martins, TH … - Human genetics, 2005 - Springer Abstract Inherited dilated cardiomyopathy (DCM) is a genetically and
phenotypically very heterogeneous dis- ease. DCM is caused by mutations in
multiple genes encoding proteins that are involved in force generation, ... Cited by 9 - Related articles - BL Direct - All 4 versions
- ►onlinejacc.org PT Ellinor, S Sasse-Klaassen, S Probst, B … - Journal of the American College of Cardiology, 2006 - Elsevier Sixty-six family members were evaluated by 12-lead electrocardiogram (ECG),
echocardiogram, and laboratory studies. Individuals with echocardiographically
documented DCM were defined as affected. Subjects were considered ... Cited by 13 - Related articles - BL Direct - All 17 versions
- ►onlinejacc.org NG Mahon, BP Madden, ALP Caforio, PM … - Journal of the American College of Cardiology, 2002 - Elsevier Over six years, 767 asymptomatic relatives of 183 consecutive patients with DCM
were evaluated: 37 (5%) had DCM and 104 (14%) had LVE (left ventricular
end-diastolic dimension >112% predicted) with normal systolic function. ... Cited by 44 - Related articles - BL Direct - All 14 versions
Y Matsumoto, T Hayashi, N Inagaki, M … - Journal of Muscle Research and Cell Motility, 2005 - Springer Page 1. Functional analysis of titin/connectin N2-B mutations found in
cardiomyopathy YUJI MATSUMOTO 1,2 , TAKEHARU HAYASHI 1 , NATSUKO ... Cited by 28 - Related articles - BL Direct - All 3 versions
RT Murphy, J Mogensen, A Shaw, T Kubo, S … - The Lancet, 2004 - Elsevier Idiopathic dilated cardiomyopathy is a common cause of heart failure. Half of
cases are believed to be hereditary, and mutations in cardiac sarcomeric
contractile protein genes have been reported with autosomal dominant ... Cited by 83 - Related articles - All 6 versions
- ►onlinejacc.org EL Burkett, RE Hershberger - Journal of the American College of Cardiology, 2005 - Elsevier Idiopathic dilated cardiomyopathy (IDC) is characterized by left ventricular
dilatation and systolic dysfunction after known causes have been excluded.
Idiopathic dilated cardiomyopathy occurring in families, or familial ... Cited by 111 - Related articles - All 9 versions
- ►oxfordjournals.org S Karkkainen, T Helio, R Miettinen, P … - European heart journal, 2004 - Eur Soc Cardiology Methods and results All 12 exons of the lamin A/C gene were screened in 18
well-characterised familial DCM patients from eastern and southern Finland and
in 72 sporadic DCM patients from eastern Finland using the PCR-SSCP method. ... Cited by 37 - Related articles - All 5 versions
- ►oxfordjournals.org S Karkkainen, T Helio, P Jaaskelainen, R … - European Journal of Heart Failure, 2004 - eurjhf.oxfordjournals.org Methods and results: We screened all coding exons of five sarcomere protein
genes (β-myosin heavy chain, -tropomyosin, troponin C, troponin I and troponin
T) in a well-characterized population of 52 DCM patients in Eastern Finland ... Cited by 14 - Related articles - All 3 versions
[CITATION] The genetic basis for cardiomyopathy: from mutation identification to mechanistic paradigms …
