- ►annals.org [PDF] DE Niewoehner, K Rice, C Cote, D Paulson, … - Annals of internal medicine, 2005 - Am Coll Physicians Prevention of Exacerbations of Chronic Obstructive Pulmonary ... Disease with
Tiotropium, a Once-Daily Inhaled ... Dennis E. Niewoehner, MD; Kathryn Rice,
MD; Claudia Cote, MD; Daniel Paulson, MD; J. Allen D. Cooper Jr., MD; Larry ... Cited by 230 - Related articles - BL Direct - All 6 versions
- ►ersj.org.uk D Dusser, ML Bravo, P Iacono - European Respiratory Journal, 2006 - ersj.org.uk The mean±SD number of exacerbations during the past year was 2.14±1.40, the
mean weekly morning peak expiratory flow (PEF) was 259.6±96.1 L·min –1 and
the mean forced expiratory volume in one second (FEV 1 ) was 1.37±0.45 L. ... Cited by 96 - Related articles - BL Direct - All 6 versions
- ►critcaremed.com V Brusasco, R Hodder, M Miravitlles, L … - British Medical Journal, 2006 - thorax.bmj.com Results: 1207 patients participated in the study (tiotropium 402, salmeterol
405, placebo 400). Compared with placebo, tiotropium but not salmeterol was
associated with a significant delay in the time to onset of the first ... Cited by 288 - Related articles - BL Direct - All 17 versions
- ►ersj.org.uk R Casaburi, DA Mahler, PW Jones, A Wanner, … - European Respiratory Journal, 2002 - ersj.org.uk Patients with stable COPD (age 65.2±8.7 yrs (mean±sd), n=921) were enrolled in
two identical randomized double-blind placebo-controlled 1-yr studies. Patients
inhaled tiotropium 18 µg or placebo (mean screening forced expiratory ... Cited by 625 - Related articles - BL Direct - All 13 versions
F Maltais, A Hamilton, D Marciniuk, P … - Chest, 2005 - chestjournal.chestpubs.org * From the Centre de Recherche (Dr. Maltais), Hôpital Laval, Institut
Universitaire de Cardiologie et de Pneumologie de l'Université Laval, Québec,
QC, Canada; Boehringer Ingelheim (Canada) Limited (Dr. Hamilton), ... Cited by 147 - Related articles - BL Direct - All 7 versions
- ►ersj.org.uk W Vincken, JA Van Noord, APM Greefhorst, TA … - European Respiratory Journal, 2002 - ersj.org.uk Screening forced expiratory volume in one second (FEV 1 ) were 1.25±0.43 L
(41.9±12.7% of the predicted value) (tiotropium) and 1.18±0.37 L (39.4±10.7%
pred) (ipratropium). Trough FEV 1 at 1 yr improved by 0.12±0.01 L with ... Cited by 607 - Related articles - BL Direct - All 13 versions
- ►ersjournals.com JA Van Noord, JL Aumann, E Janssens, JJ … - European Respiratory Journal, 2005 - Eur Respiratory Soc Compared with baseline (FEV 1 prior to the first dose in the first period),
tiotropium produced a significantly greater improvement in average daytime FEV 1
(0–12 h) than formoterol (127 versus 86 mL), while average night-time FEV ... Cited by 156 - Related articles - BL Direct - All 9 versions
- ►chestpubs.org R Casaburi, D Kukafka, CB Cooper, TJ Witek, … - Chest, 2005 - chestjournal.chestpubs.org Design: In a randomized, double-blind, placebo-controlled trial (tiotropium, n =
47; placebo, n = 44), tiotropium (18 μg qd) was administered to COPD patients
participating in 8 weeks of PR (treadmill training three times a week; ≥ ... Cited by 182 - Related articles - All 8 versions
- ►ersj.org.uk DE O'Donnell, T Fluge, F Gerken, A Hamilton … - European Respiratory Journal, 2004 - ersj.org.uk On day 42, the use of tiotropium was associated with the following effects at
pre-dose and post-dose measurements as compared to placebo: vital capacity and
inspiratory capacity (IC) increased, with inverse decreases in residual ... Cited by 418 - Related articles - BL Direct - All 6 versions
M Decramer, B Celli, DP Tashkin, RA Pauwels … - COPD: Journal of Chronic Obstructive Pulmonary …, 2004 - informahealthcare.com An accelerated loss of lung function is one of the defining characteristics of
chronic obstructive pulmonary disease (COPD). To date, the only successful
intervention shown to conclusively attenuate the loss of lung function over ... Cited by 110 - Related articles - All 10 versions
