- ►annals.org E Colman - Annals of internal medicine, 2005 - Am Coll Physicians Beginning with the passage of the Federal Food, Drug, and Cosmetic Act in 1938 and escalating
with the 1962 Kefauver-Harris amendments, increasing pressure has been placed on pharmaceutical
manufacturers to demonstrate that a drug's benefits outweigh its risks. Nowhere has the ... Cited by 36 - Related articles - BL Direct - All 9 versions
YS Hsieh, SF Yang, HL Chiou, DY … - European Journal of …, 2005 - interscience.wiley.com Amphetamine (AMPH) is known as an anorectic agent. The anorectic action of AMPH has been
attributed to its inhibitory action on hypothalamic neuropeptide Y (NPY), an appetite stimulant
in the brain. The molecular mechanisms behind this anorectic action of AMPH are still ... Cited by 8 - Related articles - BL Direct - All 4 versions
DY Kuo - J. Neurochem, 2008 - w3.csmu.edu.tw Transcriptional interruption of cAMP response element binding ... Y-mediated feeding behavior
in freely moving rats ... Yih-Shou Hsieh,* Shun-Fa Yang, Shu-Chen Chu,à Ying-Jui Ho,§
Chih-Sheng Kuo¶ and Dong-Yih Kuo** ... *Institute of Biochemistry, Chung Shan Medical ... Cited by 2 - Related articles - View as HTML - BL Direct - All 6 versions
HM Blanck, LK Khan, MK Serdula - Preventive medicine, 2004 - Elsevier Background: Despite the popularity of antiobesity medications, there is a lack of population-based
data on their use. In addition, response (termination of pill use and receipt of an
echocardiogram) to the fenfluramine and dexfenfluramine market withdrawal among the ... Cited by 16 - Related articles - All 3 versions
- ►physiology.org YS Hsieh, SF Yang, DY Kuo - American Journal of Physiology- …, 2007 - Am Physiological Soc Although amphetamine (AMPH)-induced appetite suppression has been attributed to its inhibitory
action on neuropeptide Y (NPY), an appetite neurotransmitter abundant in the brain, molecular
mechanisms underlying this effect are not well known. This study examined the possible ... Cited by 4 - Related articles - BL Direct - All 5 versions
A Astrup, I Caterson, P Zelissen, B Guy-Grand, M … - Obesity …, 2004 - 万方数据资源系统 OBJECTIVE: To examine the safety and efficacy of topiramate (TPM) for maintaining weight following
a low-calorie diet. RESEARCH METHODS AND PROCEDURES: Obese subjects (30 /=8% of
their initial weight received TPM (96 or 192 mg/d) or placebo; all were on a lifestyle ... Cited by 47 - Related articles - BL Direct - All 7 versions
- ►oxfordjournals.org [PDF] S Ogawa, DW Pfaff - Chemical senses, 1998 - Oxford Univ Press Abstract The antisense DNA method has been used successfully to block the expression of specific
genes in vivo in neuronal systems. An increasing number of studies in the last few years have
shown that antisense DNA administered directly into the brain can modify various kinds of ... Cited by 21 - Related articles - All 3 versions
YS Hsieh, SF Yang, HL Chiou, DY Kuo - Toxicology and applied pharmacology, 2006 - Elsevier Amphetamine (AMPH) is known as an anorectic agent. The mechanism underlying the anorectic
action of AMPH has been attributed to its inhibitory action on hypothalamic neuropeptide Y
(NPY), an appetite stimulant in the brain. This study was aimed to examine the molecular ... Cited by 8 - Related articles - All 5 versions
- ►shouxi.net SZ Yanovski - The New England journal of medicine, 2005 - nejm.highwire.org In 2005, a majority of adult Americans are over- weight or obese,1 putting millions of them at
in- creased risk for serious medical conditions, in- cluding cardiovascular disease, type 2 diabetes
mellitus, and certain forms of cancer. In obesity, a weight loss of 5 to 10 percent can ... Cited by 26 - Related articles - BL Direct - All 6 versions
DY Kuo - Behavioural brain research, 2003 - Elsevier Amphetamine (AMPH) is known as an anorectic agent. Repeated treatments of AMPH for several
days induced a marked anorexia on day 1 followed by a gradual return of food intake to normal
level. Previously, using daily food intake (DFI) as an indicator, we found that both ... Cited by 13 - Related articles - All 6 versions
