- ►annals.org NR Cook, JE Buring, PM Ridker - Annals of internal medicine, 2006 - Am Coll Physicians Background: While high-sensitivity C-reactive protein (hsCRP) is an independent
predictor of cardiovascular risk, global risk prediction models incorporating
hsCRP have not been developed for clinical use. ... Objective: To develop ... Cited by 186 - Related articles - BL Direct - All 7 versions
- ►ahajournals.org NR Cook - Circulation, 2007 - Am Heart Assoc The c statistic, or area under the receiver operating characteristic (ROC)
curve, achieved popularity in diagnostic testing, in which the test
characteristics of sensitivity and specificity are relevant to ... Cited by 219 - Related articles - All 10 versions
- ►stanfordhospital.org [PDF] PM Ridker, JE Buring, N Rifai, NR Cook - Jama, 2007 - Am Med Assoc You are seeing this message because your Web browser does not support basic Web
standards. Find out more about why this message is appearing and what you can do
to make your experience on this site better. ... Add to CiteULike Add to ... Cited by 237 - Related articles - BL Direct - All 14 versions
- ►annals.org DM Lloyd-Jones, K Liu, L Tian, P Greenland - Annals of internal medicine, 2006 - Am Coll Physicians Some experts propose C-reactive protein (CRP) as a screening tool for prediction
of cardiovascular disease (CVD). Many epidemiologic studies show positive
associations between elevated CRP levels and incident CVD. Assessment of ... Cited by 115 - Related articles - BL Direct - All 5 versions
MJ Pencina, RB D'Agostino, RB D'Agostino, … - Statistics in Medicine, 2008 - interscience.wiley.com Identification of key factors associated with the risk of developing
cardiovascular disease and quantification of this risk using multivariable
prediction algorithms are among the major advances made in preventive ... Cited by 178 - Related articles - BL Direct - All 2 versions
PWF Wilson, BH Nam, M Pencina, RB D' … - Archives of Internal Medicine, 2005 - Am Med Assoc Results There were 283 major CVD and 160 major coronary heart disease incident
events. Age-, sex-, and multivariable-adjusted analyses generally used CRP level
categories of less than 1, 1 to 3, and greater than 3 mg/L. In age- and sex- ... Cited by 116 - Related articles - BL Direct - All 13 versions
AR Folsom, LE Chambless, CM Ballantyne, J … - Archives of internal medicine, 2006 - archinte.highwire.org Methods Using a series of case-cohort studies, the prospective Atherosclerosis
Risk in Communities (ARIC) Study assessed the association of 19 novel risk
markers with incident CHD in 15 792 adults followed up since 1987-1989. ... Cited by 144 - Related articles - BL Direct - All 4 versions
D Smith… - Annals of internal medicine, 2006 - Am Coll Physicians The role of C-reactive protein (CRP) in cardiovascular disease risk remains
controversial, and several interrelated questions are unresolved. Although it is
clear that higher circulating CRP levels are associated with coronary heart ... Cited by 39 - Related articles - BL Direct - All 4 versions
- ►oxfordjournals.org MS Pepe, Z Feng, Y Huang, G Longton, R … - American Journal of Epidemiology, 2008 - Oxford Univ Press There are two popular statistical approaches to biomarker evaluation. One models
the risk of disease (or disease outcome) with, for example, logistic regression.
A marker is considered useful if it has a strong effect on risk. The second ... Cited by 46 - Related articles - BL Direct - All 10 versions
- ►oxfordjournals.org MS Pepe, H Janes, G Longton, W Leisenring … - American journal of epidemiology, 2004 - Oxford Univ Press A marker strongly associated with outcome (or disease) is often assumed to be
effective for classifying persons according to their current or future outcome.
However, for this assumption to be true, the associated odds ratio must be ... Cited by 257 - Related articles - BL Direct - All 14 versions
