- ►annals.org [PDF] EP Whitlock, BA Garlitz, EL Harris, TL Beil, … - Annals of internal medicine, 2006 - Am Coll Physicians Purpose: To conduct a focused systematic review of heredita- ry hemochromatosis
screening relating to 2 USPSTF criteria, the burden of suffering and the
potential effectiveness of a preven- tive intervention, to determine ... Cited by 55 - Related articles - All 6 versions
LW Powell, JL Dixon, GA Ramm, DM Purdie, … - Archives of Internal Medicine, 2006 - Am Med Assoc Background Hemochromatosis in white subjects is mostly due to homozygosity for
the common C282Y substitution in HFE. Although clinical symptoms are preventable
by early detection of the genetic predisposition and prophylactic ... Cited by 72 - Related articles - All 4 versions
- ►annals.org [PDF] B Schmitt, RM Golub, R Green - Annals of internal medicine, 2005 - Am Coll Physicians Background: Therapeutic phlebotomy for hereditary hemochro- matosis is
relatively safe and presumably efficacious when offered before cirrhosis
develops, so screening primary care patients is of substantial interest. ... Cited by 38 - Related articles - BL Direct - All 5 versions
KJ Allen, LC Gurrin, CC Constantine, NJ … - New England Journal of Medicine, 2008 - content.nejm.org Katrina J. Allen, MD, Ph.D., Lyle C. Gurrin, Ph.D., Clare C. Constantine, Ph.D.,
Nicholas J. Osborne, Ph.D., Martin B. Delatycki, MD, Ph.D., Amanda J. Nicoll,
MD, Ph.D., Christine E. McLaren, Ph.D., Melanie Bahlo, Ph.D., Amy E. ... Cited by 80 - Related articles - BL Direct - All 6 versions
- ►ru.nl [PDF] MB Delatycki, KJ Allen, AE Nisselle, V Collins … - The Lancet, 2005 - Elsevier HFE-associated hereditary haemochromatosis is a recessive, iron-overload
disorder that affects about one in 200 north Europeans and that can be easily
prevented. However, genetic screening for this disease is controversial, ... Cited by 55 - Related articles - All 4 versions
A Qaseem, M Aronson, N Fitterman, V Snow, … - Annals of internal medicine, 2005 - Am Coll Physicians Hereditary hemochromatosis is a genetic disorder of iron metabolism. Diagnosis
of hereditary hemochromatosis is usually based on a combination of various
genetic or phenotypic criteria. Decisions regarding screening are difficult ... Cited by 40 - Related articles - BL Direct - All 9 versions
- ►nih.gov CA McCune, D Ravine, K Carter, HA Jackson, … - British Medical Journal, 2006 - gut.bmj.com Background and aims: Although most cases of hereditary haemochromatosis are
associated with homozygosity for the C282Y mutation of the HFE gene, clinical
penetrance varies and other genes may modify disease expression. If so, ... Cited by 26 - Related articles - BL Direct - All 12 versions
S Dubois, KV Kowdley - Archives of Internal Medicine, 2003 - archinte.highwire.org HEREDITARY HEMOCHROMATOSIS, commonly described as human leukocyte
antigen–linked or HFE-associated hemochromatosis, is an inherited disorder of
iron metabolism leading to excessive absorption of iron from the ... Cited by 13 - Related articles - BL Direct - All 4 versions
- ►bloodjournal.org RV Andersen, A Tybjaerg-Hansen, M … - Blood, 2004 - Am Soc Hematology Hereditary hemochromatosis may be one of the most common genetic disorders among
people of Northern European descent. 3,4 Therefore, hereditary hemochromatosis
could be an ideal condition for population screening 5,6 ; however, ... Cited by 124 - Related articles - BL Direct - All 11 versions
- ►hemocromatosis.es [PDF] PC Adams, DM Reboussin, JC Barton, CE … - The New England journal of medicine, 2005 - nejm.highwire.org Results Of the 99,711 participants, 299 were homozygous for the C282Y mutation.
The estimated prevalence of C282Y homozygotes was higher in non-Hispanic whites
(0.44 percent) than in Native Americans (0.11 percent), Hispanics (0.027 ... Cited by 206 - Related articles - All 15 versions
