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Scholar Results 1 - 10 of about 101 related to Reinstein: Narrative review: protein degradation and human diseases: the ubiquitin connection. (0.19 sec) 

Narrative review: protein degradation and human diseases: the ubiquitin connection

- annals.org [PDF] 
E Reinstein, A Ciechanover - Annals of internal medicine, 2006 - Am Coll Physicians
Between the 1950s and 1980s, many scientists focused on the process by which the
genetic code is translated into proteome. However, little attention was devoted
to the mechanism responsible for protein degradation. When researchers ...
Cited by 58 - Related articles - BL Direct - All 13 versions

Diaphragm single-fiber weakness and loss of myosin in congestive heart failure rats

- physiology.org
HWH van Hees, HFM van der Heijden, CAC … - American Journal of Physiology- Heart and Circulatory …, 2007 - Am Physiological Soc
Diaphragm weakness commonly occurs in patients with congestive heart failure
(CHF) and is an independent predictor of mortality. However, the pathophysiology
of diaphragm weakness is poorly understood. We hypothesized that CHF ...
Cited by 8 - Related articles - BL Direct - All 7 versions

Drug discovery in the ubiquitin–proteasome system


G Nalepa, M Rolfe, JW Harper - Nature Reviews Drug Discovery, 2006 - nature.com
Regulated protein turnover via the ubiquitin–proteasome system (UPS) underlies
a wide variety of signalling pathways, from cell-cycle control and transcription
to development. Recent evidence that pharmacological inhibition of the ...
Cited by 99 - Related articles - BL Direct - All 3 versions

Oxidative stress of myosin contributes to skeletal muscle dysfunction in rats with chronic heart …

- physiology.org
C Coirault, A Guellich, T Barbry, JL Samuel, B … - American Journal of Physiology- Heart and Circulatory …, 2007 - Am Physiological Soc
Intrinsic muscle abnormalities affecting skeletal muscle are often reported
during chronic heart failure (CHF). Because myosin is the molecular motor of
force generation, we sought to determine whether its dysfunction ...
Cited by 16 - Related articles - BL Direct - All 5 versions

The ubiquitin-proteasome pathway in cell cycle control


SI Reed - Results and problems in cell differentiation, 2006 - 万方数据资源系统
Ubiquitin-mediated proteolysis is one of the key mechanisms underlying cell
cycle control. The removal of barriers posed by accumulation of negative
regulators, as well as the clearance of proteins when they are no longer ...
Cited by 21 - Related articles - BL Direct - All 2 versions

Neuroscience: parkin and its substrates


C Haass, PJ Kahle - Science, 2001 - sciencemag.org
Note to users. If you're seeing this message, it means that your browser cannot
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using a browser that does not support current Web standards. Find out more ...
Cited by 7 - Related articles - BL Direct - All 3 versions

Parkin and its substrates


C Haass, PJ Kahle - Science, 2001 - cmbi.bjmu.edu.cn
Parkinson's disease (PD) has long been considered a textbook example of a
sporadic neurodegenerative disorder. Patients with PD have characteristic motor
deficits caused by loss of dopaminergic neurons in the brain's ...
Cited by 6 - Related articles - Cached - All 3 versions

The redox regulation of PI 3-kinase-dependent signaling


NR Leslie - Antioxidants & Redox Signaling, 2006 - liebertonline.com
INTRODUCTION T HE COMPLEX BEHAVIOR of the cells of higher multicellular
organisms is regulated by multilayered signal transduc- tion pathways and
networks that integrate information from several sources to control a ...
Cited by 28 - Related articles - BL Direct - All 5 versions

Activation of ubiquitin-proteasome pathway in the diaphragm in chronic obstructive …

- atsjournals.org [PDF] 
CAC Ottenheijm, L Heunks, YP Li, B Jin, R … - American journal of respiratory and critical care …, 2006 - Am Thoracic Soc
Page 1. ACTIVATION OF UBIQUITIN-PROTEASOME PATHWAY IN THE DIAPHRAGM IN
CHRONIC OBSTRUCTIVE PULMONARY DISEASE Coen AC Ottenheijm 1 ...
Cited by 32 - Related articles - BL Direct - All 9 versions

[CITATION] Inspiratory muscle weakness and dyspnea in chronic heart failure. Am Rev Respir Dis 1992; …


C McParland, B Krishnan, Y Wang, CG … - J Physiol, 1996
Cited by 3 - Related articles


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