- ►annals.org [PDF] D Menzies, M Pai, G Comstock - Annals of internal medicine, 2007 - Am Coll Physicians Background: Until recently, the tuberculin skin test was the only test for detecting latent tuberculosis
(TB) infection, but 2 ex vivo interferon- release assays (IGRAs) are now commercially
licensed. ... Purpose: To estimate sensitivity, specificity, and reproducibility of IGRAs ( ... Cited by 300 - Related articles - BL Direct - All 3 versions
- ►oxfordimmunotec.com [PDF] G Ferrara, M Losi, R D'Amico, P Roversi, R Piro, M … - The Lancet, 2006 - Elsevier Overall agreement with the skin test was similar (T-SPOT.TB κ=0·508, QuantiFERON-TB Gold
κ=0·460), but fewer BCG-vaccinated individuals were identified as positive by the two blood assays
than by the tuberculin skin test (p=0·003 for T-SPOT.TB and p<0.0001 for ... Cited by 269 - Related articles - All 16 versions
- ►annals.org [PDF] M Pai, A Zwerling, D Menzies - Annals of internal medicine, 2008 - Am Coll Physicians Background: Interferon- –release assays (IGRAs) are alternatives to the tuberculin skin test
(TST). A recent meta-analysis showed that IGRAs have high specificity, even among populations
that have received bacille Calmette–Guérin (BCG) vaccination. Sensitivity was ... Cited by 125 - Related articles - All 9 versions
GH Mazurek, J Jereb, P LoBue, MF Iademarco, B … - MMWR Recomm Rep, 2005 - cdc.gov On May 2, 2005, a new in vitro test, QuantiFERON ® -TB Gold (QFT-G, Cellestis Limited,
Carnegie, Victoria, Australia), received final approval from the US Food and Drug Administration
as an aid for diagnosing Mycobacterium tuberculosis infection. This test detects the ... Cited by 307 - Related articles - Cached - All 9 versions
- ►171.66.122.149 SM Arend, SFT Thijsen, E Leyten, JJM … - American journal of …, 2007 - 171.66.122.149 Methods: When a supermarket employee with smear-positive tuberculosis had infected most
close contacts, a contact investigation among more than 20,000 customers was performed. We
recruited subjects randomly on the day of TST administration (n = 469) and subjects with ... Cited by 113 - Related articles - BL Direct - All 5 versions
M Farhat, C Greenaway, M Pai, D … - The International Journal …, 2006 - ingentaconnect.com BACKGROUND: Despite certain drawbacks, the tubercu- lin skin test (TST) remains in widespread
use. Important advantages of the TST are its low cost, simplicity and in- terpretation based on
extensive published literature. How- ever, TST specificity is reduced by bacille Calmette- ... Cited by 122 - Related articles - BL Direct - All 4 versions
- ►atsjournals.org L Richeldi - American journal of respiratory and critical care …, 2006 - Am Thoracic Soc Targeted testing and treatment of individuals with latent tuberculosis infection at increased risk
of progression to active disease is a key element of tuberculosis control. This strategy is limited
by the poor specificity of the tuberculin skin test in populations vaccinated with bacille ... Cited by 174 - Related articles - BL Direct - All 6 versions
- ►chestpubs.org A Lalvani - Chest, 2007 - chestjournal.chestpubs.org The century-old tuberculin skin test (TST) was until recently the only means of diagnosing latent
tuberculosis infection (LTBI). Recent advances in mycobacterial genomics and human cellular
immunology have resulted in two new blood tests that detect tuberculosis infection by ... Cited by 108 - Related articles - BL Direct - All 9 versions
M Pai, LW Riley, JM Colford - The Lancet infectious diseases, 2004 - Elsevier A major challenge in tuberculosis control is the diagnosis and treatment of latent tuberculosis
infection. Until recently, there were no alternatives to the tuberculin skin test (TST) for diagnosing
latent tuberculosis. However, an alternative has now emerged in the form of a new in-vitro ... Cited by 429 - Related articles - All 11 versions
I Brock, M Ruhwald, B Lundgren, H Westh, LR … - Respiratory …, 2006 - biomedcentral.com Although tuberculosis (TB) is a minor problem in Denmark, severe and complicated cases occur
in HIV positive. Since the new M. tuberculosis specific test for latent TB, the QuantiFERON-TB
In-Tube test (QFT-IT) became available the patients in our clinic have been screened for ... Cited by 116 - Related articles - Cached - All 10 versions
