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Scholar Results 1 - 10 of about 101 related to Zinman: The effect of adding exenatide to a thiazolidinedione in suboptimally controlled.... (0.09 sec) 

The effect of adding exenatide to a thiazolidinedione in suboptimally controlled type 2 …

- annals.org [PDF] 
B Zinman, BJ Hoogwerf, S Duran Garcia, DR … - Annals of internal medicine, 2007 - Am Coll Physicians
Background: Exenatide therapy is effective in combination with metformin or
sulfonylureas for treating type 2 diabetes. Thiazo- lidinediones (TZDs) also are
commonly used, but the efficacy of exenatide with a TZD has not been reported.
Cited by 119 - Related articles - BL Direct - All 5 versions

A comparison of twice-daily exenatide and biphasic insulin aspart in patients with type 2 …


MA Nauck, S Duran, D Kim, D Johns, J … - Diabetologia, 2007 - Springer
Abstract Aims/hypothesis The aim of this 52-week, open-label, non- inferiority
trial was to compare the safety and efficacy of exenatide (an incretin mimetic)
with that of biphasic insulin aspart. Materials and methods Patients on ...
Cited by 132 - Related articles - BL Direct - All 4 versions

Effects of once-weekly dosing of a long-acting release formulation of exenatide on glucose …

- diabetesjournals.org
D Kim, L MacConell, D Zhuang, PA Kothare, … - Diabetes Care, 2007 - Am Diabetes Assoc
RESULTS—From baseline to week 15, exenatide LAR reduced mean ± SE A1C by
−1.4 ± 0.3% (0.8 mg) and −1.7 ± 0.3% (2.0 mg), compared with +0.4 ± 0.3%
with placebo LAR (P < 0.0001 for both). A1C of ≤7% was achieved by 36 and ...
Cited by 127 - Related articles - BL Direct - All 5 versions

Exenatide effects on diabetes, obesity, cardiovascular risk factors and hepatic biomarkers in …


DC Klonoff, JB Buse, LL Nielsen, X Guan, … - Current Medical Research and Opinion®, 2007 - informahealthcare.com
Background: Exenatide, an incretin mimetic for adjunctive treatment of type 2
diabetes (T2DM), reduced hemoglobin A1c (A1C) and weight in clinical trials. The
objective of this study was to evaluate the effects of ≥3 years exenatide ...
Cited by 91 - Related articles - BL Direct - All 7 versions

Metabolic effects of two years of exenatide treatment on diabetes, obesity, and hepatic …


JB Buse, DC Klonoff, LL Nielsen, X Guan, … - Clinical therapeutics, 2007 - Elsevier
For this interim analysis, data were pooled from patients who completed 1 of
three 30-week, multicenter, double-blind, placebo-controlled trials and their
open-label extensions. In the initial trials, subjects were randomized to ...
Cited by 91 - Related articles - All 3 versions

Exenatide versus insulin glargine in patients with suboptimally controlled type 2 diabetes: a …

- annals.org [PDF] 
RJ Heine, LF Van Gaal, D Johns, MJ Mihm, … - Annals of internal medicine, 2005 - Am Coll Physicians
Patients: 551 patients with type 2 diabetes and inadequate gly- cemic control
(defined as hemoglobin A1c level ranging from 7.0% to 10.0%) despite combination
metformin and sulfonylurea therapy. Intervention: Exenatide, 10 g twice ...
Cited by 329 - Related articles - BL Direct - All 7 versions

Interim analysis of the effects of exenatide treatment on A1C, weight and cardiovascular risk …


L Blonde, EJ Klein, J Han, B Zhang, SM Mac, … - Diabetes, Obesity & Metabolism, 2006 - pt.wkhealth.com
Results: Patients completed 82 weeks of exenatide treatment [n = 314, 63% M, age
56 ± 10 years, weight 99 ± 21 kg, body mass index 34 ± 6 kg/m 2 , A1C 8.3 ±
1.0% (mean ± SD)]. Reduction in A1C from baseline to week 30 [-0.9 ± 0.1% ...
Cited by 172 - Related articles - BL Direct - All 6 versions

Addition of vildagliptin to insulin improves glycaemic control in type 2 diabetes


V Fonseca, A Schweizer, D Albrecht, MA … - Diabetologia, 2007 - Springer
Abstract Aims/hypothesis Type 2 diabetes is difficult to manage in patients with
a long history of disease requiring insulin therapy. Moreover, addition of most
currently available oral antidiabetic agents increases the risk of ...
Cited by 104 - Related articles - BL Direct - All 4 versions

Liraglutide, a long-acting human glucagon-like peptide-1 analog, given as monotherapy …


T Vilsbøll, M Zdravkovic, T Le-Thi, T Krarup, … - Diabetes Care, 2007 - Am Diabetes Assoc
Main inclusion criteria were patients aged ≥18 years with type 2 diabetes and
A1C ≥7.5 and ≤10.0% (diet) or ≥7.0 and ≤9.5% (mono–oral antidiabetes
drug); previous therapy was discontinued. Fasting plasma glucose (FPG) at ...
Cited by 116 - Related articles - BL Direct - All 5 versions

Efficacy and safety of incretin therapy in type 2 diabetes: systematic review and meta- …

- wanfang.gov.tw [DOC] 
RE Amori, J Lau, AG Pittas - Jama, 2007 - Am Med Assoc
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Cited by 240 - Related articles - BL Direct - All 8 versions


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