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Scholar Results 1 - 10 of about 101 related to Chan: Treatment of hepatitis B e antigen positive chronic hepatitis with telbivudine or adefovir:.... (0.11 sec) 

Treatment of hepatitis B e antigen positive chronic hepatitis with telbivudine or adefovir: a …

- annals.org
HLY Chan, EJ Heathcote, P Marcellin, CL Lai, … - Annals of Internal Medicine, 2007 - Am Coll Physicians
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Background: The efficacy of nucleoside and nucleotide analogues for ...
Cited by 74 - Related articles - BL Direct - All 9 versions

Telbivudine versus lamivudine in patients with chronic hepatitis B


CL Lai, E Gane, YF Liaw, CW Hsu, S … - The New England Journal of Medicine, 2007 - nejm.highwire.org
From the University Department of Med- icine, Queen Mary Hospital, Hong Kong
(C.-LL); Middlemore Hospital, Auckland, New Zealand (EG); Chang Gung Memo- rial
Hospital, Chang Gung University Col- lege of Medicine, Taipei, Taiwan ...
Cited by 175 - Related articles - BL Direct - All 6 versions

Lamivudine compared with lamivudine and adefovir dipivoxil for the treatment of HBeAg- …

- radiologysource.org
JJY Sung, JY Lai, S Zeuzem, WC Chow, EJ … - Journal of Hepatology, 2008 - Elsevier
Time-weighted average change in serum HBV DNA from baseline up to week 16 was
−4.20 log 10 copies/mL for both groups (p = 0.936). At week 104, median serum
HBV DNA change from baseline (log 10 copies/mL) for monotherapy and ...
Cited by 52 - Related articles - All 18 versions

A 1-Year Trial of Telbivudine, Lamivudine, and the Combination in Patients With Hepatitis B …

- sebivo.com.ua [PDF] 
CL Lai, N Leung, EK Teo, M Tong, F Wong, … - Gastroenterology, 2005 - Elsevier
Background & Aims: A previous 4-week trial of telbivudine in patients with
chronic hepatitis B indicated marked antiviral effects with good tolerability,
leading to the present 1-year phase 2b trial. Methods: This randomized, ...
Cited by 269 - Related articles - All 5 versions

Pharmacokinetics of telbivudine in healthy subjects and absence of drug interaction with …

- nih.gov
XJ Zhou, BA Fielman, DM Lloyd, GC Chao, … - Antimicrobial agents and chemotherapy, 2006 - aac.highwire.org
Two phase I studies were conducted to assess the plasma pharmacokinetics of
telbivudine and potential drug-drug interactions between telbivudine (200 or 600
mg/day) and lamivudine (100 mg/day) or adefovir dipivoxil (10 mg/day) in ...
Cited by 28 - Related articles - BL Direct - All 9 versions

Report of an international workshop: roadmap for management of patients receiving oral …

- ucsf.edu [PDF] 
EB Keeffe, S Zeuzem, RS Koff, DT Dieterich, R … - Clinical Gastroenterology and Hepatology, 2007 - Elsevier
An international group of experienced hepatologists and virologists conducted a
single-day workshop to review the management of patients with chronic hepatitis
B receiving treatment with oral nucleosides or nucleotides. Guidelines ...
Cited by 121 - Related articles - All 13 versions

[CITATION] weeks combination of adefovir dipivoxil plus emtricitabine vs. adefovir dipivoxil monotherapy …


CK Hui, HY Zhang, S Bowden, S Locarnini, … - J Hepatol, 2008
Cited by 32 - Related articles

2-Year GLOBE trial results: telbivudine is superior to lamivudine in patients with chronic …

- journalacs.org
YF Liaw, E Gane, N Leung, S Zeuzem, Y Wang … - Gastroenterology, 2009 - Elsevier
The therapeutic response to telbivudine was superior to that of lamivudine in
HBeAg-positive (63% vs 48%; P < .001) and HBeAg-negative (78% vs 66%; P = .007)
patients. HBeAg-positive patients given telbivudine also had better ...
Cited by 42 - Related articles - All 8 versions

Telbivudine versus lamivudine in Chinese patients with chronic hepatitis B: Results at 1 year …


J Hou, YK Yin, D Xu, D Tan, J Niu, X Zhou, Y … - Hepatology, 2008 - interscience.wiley.com
Chronic hepatitis B and its life-threatening sequelae are highly prevalent in
China. There is a need for effective new therapies to suppress hepatitis B virus
(HBV) replication and ameliorate liver disease. In this study, we compared ...
Cited by 41 - Related articles - BL Direct - All 4 versions

A dose-finding study of once-daily oral telbivudine in HBeAg-positive patients with chronic …


CL Lai, SG Lim, NA Brown, XJ Zhou, DM … - Hepatology, 2004 - interscience.wiley.com
Current therapy for chronic hepatitis B is suboptimal as a result of limited
durable response rates, cumulative viral resistance, and/or poor tolerability.
Telbivudine has potent antiviral activity against hepatitis B virus (HBV) ...
Cited by 99 - Related articles - All 3 versions


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