- ►annals.org [PDF] S Lanzkron, JJ Strouse, R Wilson, MC Beach, … - Annals of Internal Medicine, 2008 - Am Coll Physicians Background: Hydroxyurea is the only approved drug for treatment of sickle cell
disease. ... Objective: To synthesize the published literature on the efficacy,
effectiveness, and toxicity of hydroxyurea when used in adults with sickle ... Cited by 18 - Related articles - BL Direct - All 4 versions
JJ Strouse, S Lanzkron, MC Beach, C Haywood … - Pediatrics, 2008 - Am Acad Pediatrics METHODS. Medline, Embase, TOXLine, and the Cumulative Index to Nursing and
Allied Health Literature through June 2007 were used as data sources. We
selected randomized trials, observational studies, and case reports ... Cited by 9 - Related articles - All 4 versions
OW Brawley, LJ Cornelius, LR Edwards, VN … - Annals of Internal Medicine, 2008 - Am Coll Physicians National Institutes of Health consensus and state-of-the- science statements are
prepared by independent panels of health professionals and public
representatives on the basis of 1) the results of a systematic literature ... Cited by 25 - Related articles - BL Direct - All 3 versions
Y Saunthararajah, R Molokie, S Saraf, S … - British journal of haematology, 2008 - ncbi.nlm.nih.gov 1: Br J Haematol. 2008 Apr;141(1):126-9. Clinical effectiveness of decitabine
in severe sickle cell disease. Saunthararajah Y, Molokie ... Cited by 5 - Related articles - BL Direct - All 3 versions
P Vicari, A Barretto de Mello, MS Figueiredo - American journal of hematology, 2005 - interscience.wiley.com Fetal hemoglobin (HbF) inhibits the polymerization of sickle hemoglobin,
modulating the clinical features of sickle cell anemia (SCA). Hydroxyurea (HU)
therapy can increase the HbF level, although its production can be ... Cited by 9 - Related articles - All 3 versions
M Westerman, A Pizzey, J Hirschman, M Cerino … - British Journal of Haematology, 2008 - interscience.wiley.com Levels of circulating red blood cell (RBC)-derived vesicles are increased in
sickle cell anaemia (SCA) and thalassaemia intermedia (TI) but the mechanisms,
effects and controlling factors may differ. This study found that levels of ... Cited by 7 - Related articles - All 4 versions
- ►hematologylibrary.org R Mabaera, MR Greene, CA Richardson, SJ … - Blood, 2008 - bloodjournal.hematologylibrary.org 5-azacytidine (5-Aza) is a potent inducer of fetal hemoglobin (HbF) in people
with β-thalassemia and sickle cell disease. Two models have been proposed to
explain this activity. The first is based on the drug's ability to inhibit ... Cited by 17 - Related articles - BL Direct - All 5 versions
OS Platt - N Engl J Med, 2008 - terapiaintensivacali.com There are about 50,000 people in the United States who are homozygous for the
sickle hemoglobin gene and thus have sickle cell anemia. Sickle cell anemia is
primar- ily seen in persons of African heritage, about 1 in 14 of whom is ... Cited by 28 - Related articles - View as HTML - BL Direct - All 8 versions
C Thauvin-Robinet, C Maingueneau, E Robert, … - Leukemia: official journal of the Leukemia Society of …, 2001 - ncbi.nlm.nih.gov 1: Leukemia. 2001 Aug;15(8):1309-11. Exposure to hydroxyurea during pregnancy:
a case series. Thauvin-Robinet C, Maingueneau C, Robert ... Cited by 11 - Related articles - BL Direct
