PD Phatak, HL Bonkovsky, KV Kowdley - Ann Intern Med, 2008 - Am Coll Physicians The discovery of the HFE gene in 1996 heralded a decade of major advances in the
understanding of the mechanisms that control iron absorption and body iron
stores. A genetic definition of the com- mon form of hereditary ... Cited by 7 - Related articles - All 3 versions
JK Olynyk, D Trinder, GA Ramm, RS Britton, … - Hepatology (Baltimore, Md.), 2008 - pubmedcentral.nih.gov Following the discovery of the HFE gene in 1996 and its linkage to the iron
overload disorder hereditary hemochromatosis (HH) there have been profound
developments in our understanding of the pathogenesis of the biochemical ... Cited by 6 - Related articles - All 4 versions
G Gagné, D Reinharz, N Laflamme, PC … - Clin Genet, 2007 - interscience.wiley.com Screening for hereditary hemochromatosis, although largely discussed, is not yet
implemented in clinical practice. We evaluated the cost-effectiveness of 165
hemochromatosis population-screening algorithms involving two or three of ... Cited by 7 - Related articles - All 5 versions
S Von Delius, C Lersch, E Schulte-Frohlinde, … - Z Gastroenterol, 2006 - thieme-connect.com The occurrence of primary hepatocellular carcinoma (HCC) in patients with
hereditary hemochromatosis (HH) is well known. Thereby, the development of liver
cirrhosis seems to be a prerequisite. Whether or not a hepatic iron ... Cited by 7 - Related articles - BL Direct - All 4 versions
N Sunderland - uwomeds.com A 26 year old female fashion student getting lab work for allergy testing was
incidentally found to have significantly increased serum transferrin and
ferritin levels. Subsequent genetic testing revealed homozygous mutation ... Related articles - View as HTML
ND Aspects - gmbahia.ufba.br Recebido em 27/06/2009 Aceito em 06/06/2009 Endereço para correspondência:
ALLEE LA BRUYERE Nº 2 - RENNES - FRACE. E-mail: pierre.brissot@univ-rennes1.fr.
Financial support: Association Fer et Foie and EEC FP6 Euroiron1, ... Related articles - View as HTML - All 2 versions
J Alexander, KV Kowdley - Genetics in Medicine, 2009 - journals.lww.com Abstract. In populations of northern European descent, the p.C282Y mutation in
the HFE gene is highly prevalent, and HFE-associated hered- itary
hemochromatosis is the most common type of inherited iron overload ... Related articles - All 2 versions
- ►friendsoftheslulc.com [PDF] BR Bacon, RS Britton - The New England Journal of Medicine, 2008 - nejm.highwire.org To determine the prevalence of HFE-related hereditary hemochromatosis and its
signs and symptoms, HFE genotyping was performed in several cross-sectional
screening studies. 3 , 4 , 5 , 6 These studies clearly showed that the ... Cited by 8 - Related articles - BL Direct - All 5 versions
- ►cdc.gov [PDF] SD Grosse, WH Rogowski, LF Ross, MC … - Public Health Genomics, 2009 - content.karger.com Background: Proposals for population screening for genetic diseases require
careful scrutiny by decision makers because of the potential for harms and the
need to demonstrate benefits commensurate with the opportunity cost of ... Cited by 1 - Related articles - All 7 versions
