IH Fox, WN Kelley - Annals of Internal Medicine, 1971 - annals.org.p.angrylapdog.com The intracellular concentration of phosphoribosylpyrophosphate (PRPP), a high-energy 1,5-substituted
ribose sugar, has been demonstrated to have a critical role in the regulation of purine metabolism
in man. Increased intracellular ... Cited by 106 - Related articles - All 3 versions
- ►jbc.org [PDF] FM Rosenbloom, JF Henderson, IC Caldwell, WN … - Journal of Biological …, 1968 - ASBMB THE JOURNAL or &OLOGICAL CHEMISTRY Vol. 243, No. 6, Issue of March 26, pp.1166-1173,1968 Printed in
USA ... Biochemical Bases of Accelerated Purine Biosynthesis de Nova ... FREDERICK M. ROSENBLOOMS
From the National Institute of ... Cited by 137 - Related articles - All 3 versions
- ►jbc.org [PDF] IH Fox, WN Kelley - Journal of Biological Chemistry, 1971 - ASBMB Magnesium was the most effective divalent cation at both high and low concentrations. No requirement
for potassium was found. The pH optimum was '7.2 to 7.4. The isoelec- tric point was 4.7 f 0.2. With
the usual substrates, ATP and ... Cited by 81 - Related articles - All 2 versions
MA Becker, LJ Meyer, AW Wood, JE Seegmiller - Science, 1973 - sciencemag.org In hemolyzates from red cells of two brothers with purine overproduction and gout, activity of
phosphoribosylpyrophosphate synthetase is more than twofold greater than that measured in normal or
other gouty individuals. The ... Cited by 63 - Related articles - All 4 versions
TSAIFAN YU, M BALIS, TA KRENITSKY, J … - Annals of Internal …, 1972 - Am Coll Physicians In a survey of 425 cases of hyperuricemia with gouty arthritis or uric acid stone, or both, we found
partial deficiency of HG PRTase, a newly recognized cause of these manifestations, in only 7
subjects, of whom 5 were members of ... Cited by 42 - Related articles - All 2 versions
[CITATION] Essential role of phosphoribosylpyrophosphate (PRPP) in regulation of purine …
IH Fox, JB Wyngaarden, WN Kelley - The New England journal of …, 1970 - ncbi.nlm.nih.gov 1: N Engl J Med. 1970 Nov 26;283(22):1177-82. Depletion of erythrocyte phosphoribosylpyrophosphate in
man. Fox IH, Wyngaarden JB, Kelley WN. Publication Types: In Vitro. Mesh Terms: Administration, Oral;
Adult; Allopurinol/administration & dosage; Allopurinol/adverse effects; Allopurinol/metabolism; ... Cited by 65 - Related articles
O Sperling, P Boer, S Persky-Brosh, E Kanarek, A … - Revue européenne d' … - ncbi.nlm.nih.gov 1: Rev Eur Etud Clin Biol. 1972 Aug-Sep;17(7):703-6. Altered kinetic property of erythrocyte
phosphoribosylpsyrophosphate synthetase in excessive purine production. Sperling O, Boer
P, Persky-Brosh S, Kanarek E, De Vries A. Mesh Terms: Adenosine ... Cited by 57 - Related articles - All 2 versions
- ►jbc.org [PDF] EW Holmes, JA McDonald, JM McCord, JB … - Journal of Biological …, 1973 - ASBMB Michaelis-Menten substrate kinetics were observed with apparent K m values of 0.48 mm for
PP-ribose-P and 1.6 mm for glutamine. Human PP-ribose-P amidotransferase has an absolute requirement
for a divalent cation, with the ... Cited by 90 - Related articles - All 3 versions
