… , MA LUTZNER, BW FESTOFF, HG COON - Annals of internal …, 1974 - Am Coll Physicians Xeroderma pigmentosum is a hereditary disease clinically manifested primarily on sun-exposed
skin, which develops abnormal pigmentation and malignant tumors. Mental retardation,
areflexia, and other neurological abnormalities are seen in some patients. Only one ... Cited by 465 - Related articles - All 3 versions
JE Cleaver - 1968 - nature.com Normal skin fibroblasts can repair ultraviolet radiation damage to DNA by inserting new bases
into DNA in the form of small patches. Cells from patients with the hereditary disease xeroderma
pigmentosum carry a mutation such that repair replication of DNA is either absent or ... Cited by 1061 - Related articles - All 4 versions
- ►pnas.org [PDF] AR Lehman, S Kirk-Bell, CF Arlett, MC … - Proceedings of the …, 1975 - National Acad Sciences Page 1. Proc. Nat. Acad. Sci. USA Vol. 72, No. 1, pp. 219-223, January 1975 Xeroderma
Pigmentosum Cells with Normal Levels of Excision Repair Have a Defect in DNA Synthesis after
UV-Irradiation (postreplication repair/alkaline sucrose gradients/human fibroblasts/caffeine) ... Cited by 345 - Related articles - All 8 versions
JE Cleaver, D Bootsma - Annual Review of Genetics, 1975 - Annual Reviews Xeroderma pigmentosum (XP) is an autosomal recessive human skin disease whose outstanding
clinical characteristic is a marked predisposition to develop skin cancers after exposure to
sunlight. This disease representll a unique conjunc tion of both genetic and ... Cited by 277 - Related articles - All 4 versions
AD Andrews, SF Barrett, JH … - Proceedings of the …, 1978 - National Acad Sciences Proc. Nati. Acad. Sci. USA Vol. 75, No. 4, pp. 1984-1988, April 1978 Medical Sciences ... Xeroderma
pigmentosum neurological abnormalities correlate with colony-forming ability after ultraviolet
radiation ... (DNA repair/premature aging/carcinogenesis/acute sun sensitivity/ ... Cited by 149 - Related articles - All 8 versions
EA De Weerd-Kastelein, W Keijzer, D Bootsma - Nature: New biology, 1972 - ncbi.nlm.nih.gov 1: Nat New Biol. 1972 Jul 19;238(81):80-3. Genetic heterogeneity of xeroderma
pigmentosum demonstrated by somatic cell hybridization. De Weerd-Kastelein EA,
Keijzer W, Bootsma D. Mesh Terms: Cell Fusion; DNA/biosynthesis; ... Cited by 174 - Related articles - All 2 versions
KH Kraemer, HG Coon, RA Petinga, SF … - Proc Natl Acad Sci …, 1975 - National Acad Sciences Page 1. Proc. Nat. Acad. Sci. USA Vol. 72, No. 1, pp. 59-63, January 1975 Genetic
Heterogeneity in Xeroderma Pigmentosum: Complementation Groups and Their
Relationship to DNA Repair Rates (ultraviolet radiation/mutations ... Cited by 96 - Related articles - All 5 versions
KH Kraemer - Archives of Dermatology, 1980 - archderm.highwire.org Xeroderma pigmentosum (XP) is a rare autosomal recessive disease (frequency, one to four
per million) in which affected individuals exhibit sun sensitivity, cutaneous pigmentary ab-
normalities, and a high incidence of skin cancer.1-4 In addition, some patients with XP ... Cited by 209 - Related articles - All 5 versions
JE Cleaver - Journal of Investigative Dermatology, 1972 - nature.com The subjects are three patients with distinct symptoms of xeroderma pigmentosum (XP) in which
the cultured fibroblasts are different from those usually found in this disease. Ordinarily, XP fibroblasts
are extremely sensitive to ultraviolet (UV) light and perform reduced amounts of repair ... Cited by 127 - Related articles - All 2 versions
KH Kraemer, MM Lee, J Scotto - Archives of dermatology, 1987 - archderm.highwire.org Page 1. Xeroderma Pigmentosum Cutaneous, Ocular, and Neurologic Abnormalities
in 830 Published Cases Kenneth H. Kraemer, MD; Myung M. Lee; Joseph Scotto,
MS \s=b\ Quantitative frequencies of clinical abnormalities in ... Cited by 525 - Related articles - All 4 versions
