M Rozencweig, H VON, D DANIEL, M … - Annals of Internal …, 1977 - Am Coll Physicians Cis-diamminedichloroplatinum (II) (DDP) leads the series of platinum coordination
complexes, a new class of cytotoxic agents. The antitumor and toxic effects of this drug are
discussed. It has displayed encouraging results in testicular tumors. The drug's ... Cited by 259 - Related articles - All 2 versions
DM Hayes, E Cvitkovic, RB Golbey, E … - CA A Cancer Journal … - interscience.wiley.com A clinical trial was undertaken to improve the therapeutic index of cis-plati-num diammine dichloride
with a concomitantly administered mannitol induced diuresis. Sixty patients, heavily
pretreated, were entered; fifty-one are evaluable. The technique of concomitant osmotic ... Cited by 382 - Related articles - All 2 versions
[CITATION] Cis-diamminedichloro-platinum (11): A New Anticancer Drug
- ►aacrjournals.org [PDF] RC DeConti, BR Toftness, RC Lange, WA Creasey - Cancer Research, 1973 - AACR In 1965, Rosenberg (17) first inadvertently demonstrated that platinum compounds inhibit cell
division in Esche- richia coli. Since then, various studies have defined the chemistry of a number
of derivatives and demonstrated antineoplastic activity in many animal tumor-screening ... Cited by 226 - Related articles - All 2 versions
M Dentino, FC Luft, MN Yum, SD Williams, … - CA A Cancer Journal … - interscience.wiley.com To examine CDDP induced nephrotoxicity in patients with testicular carcinoma, we measured
renal function prior to therapy and at six month intervals for twelve months in fifteen patients and
twenty-four months in seven patients. CDDP was given iv at 20 mg/M 2 per day for five ... Cited by 194 - Related articles
NE Madias, JT Harrington - The American journal of medicine, 1978 - ncbi.nlm.nih.gov 1: Am J Med. 1978 Aug;65(2):307-14. Platinum nephrotoxicity. Madias NE, Harrington
JT. Platinum coordination complexes have recently been introduced in cancer
chemotherapy with considerable success. However, significant ... Cited by 280 - Related articles
JOND BLACHLEY, JB HILL - Annals of Internal Medicine, 1981 - Am Coll Physicians Cisplatin is a coordinate metal complex with significant antineoplastic activity and various adverse
effects, including acute and chronic renal insufficiency and renal magnesium wasting. Nephrotoxicity
may occur in as many as 50% to 75% of patients receiving the drug, and is apparently ... Cited by 182 - Related articles - All 3 versions
DD Von Hoff, R Schilsky, CM Reichert, RL Reddick, … - Cancer treatment … - ncbi.nlm.nih.gov Administration of cis-dichlorodiammineplatinum(II) may be associated with a number of serious
side effects, including nephrotoxicity, gastroeintestinal side effects (nausea, vomiting, and
diarrhea), myelosuppression, and occasional transient elevations in liver function tests. In ... Cited by 322 - Related articles
JC Gonzalez-Vitale, DM Hayes, E Cvitkovic, … - CA A Cancer Journal … - interscience.wiley.com The pathologic changes induced by Cis-platinum (II) diamminedichloride (CPDD) therapy in
the kidneys are described in 12 patients with solid tumors and malignant lymphomas. According
to dosage of CPDD the patients were divided into two groups: 1) low-dose group - 0.5-2 ... Cited by 183 - Related articles - All 2 versions
LH Einhorn, SD Williams - The New England journal of medicine, 1979 - ncbi.nlm.nih.gov 1: N Engl J Med. 1979 Feb 8;300(6):289-91. The role of cis-platinum in solid-tumor
therapy. Einhorn LH, Williams SD. Publication Types: Research Support, US Gov't,
PHS; Review. Mesh Terms: Age Factors; Antineoplastic Agents ... Cited by 99 - Related articles - All 2 versions
