RA KREISBERG - Annals of Internal Medicine, 1978 - Am Coll Physicians New concepts concerning the pathogenesis and therapy of diabetic ketoacidosis are
reviewed. The regulation of ketogenesis by intrahepatic enzymic processes and the roles of insulin
deficiency or glucagon or other counterregulatory hormone excess are summarized. ... Cited by 128 - Related articles - All 2 versions
AE KITABCHI, V AYYAGARI, SMO … - Annals of Internal …, 1976 - Am Coll Physicians The effect of low-dose intramuscular insulin therapy was compared with that of high-dose insulin
therapy by intravenous and subcutaneous routes in 48 patients with diabetic ketoacidosis. A
simplified protocol was devised to compare efficacy of the two methods of therapy in a ... Cited by 103 - Related articles - All 2 versions
JN Fisher, MN Shahshahani, AE Kitabchi - New England Journal of …, 1977 - content.nejm.org Since in normal persons the hypoglycemic effect of low-dose intramuscular exceeds that of subcutaneous
insulin we studied the effect of routes of insulin therapy in diabetic ketoacidosis. Forty-five patients
with diabetic ketoacidosis entered a randomized prospective protocol with insulin ... Cited by 104 - Related articles - All 2 versions
AE Kitabchi, R Young, H Sacks, L Morris - Annual Review of Medicine, 1979 - Annual Reviews Several comprehensive reviews (1-5) on diabetic ketoacidosis (DKA) have recently appeared
in which not only has the much-debated issue of low dose insulin therapy been covered, but
also controversial subjects such as patho genesis of DKA, supportive therapy, and insulin ... Cited by 39 - Related articles - All 3 versions
LR MORRIS, MB MURPHY, AE … - Annals of internal …, 1986 - Am Coll Physicians Twenty-one adult patients with severe diabetic ketoacidosis entered a randomized prospective
protocol in which variable doses of sodium bicarbonate, based on initial arterial pH (6.9 to
7.14), were administered to 10 patients (treatment group) and were withheld from 11 ... Cited by 170 - Related articles - All 5 versions
JN FISHER, AE KITABCHI - Journal of Clinical Endocrinology & …, 1983 - Endocrine Soc The use of phosphate therapy in the management of diabetic ketoacidosis (DKA) has been
controversial, particularly with respect to the effect of phosphate intermediates on tissue
oxygenation. In a prospective randomized study we evaluated the effect of phosphate (8.5 ... Cited by 120 - Related articles - All 2 versions
MANS OH, HJ CARROLL, DA GOLDSTEIN … - Annals of Internal …, 1978 - Am Coll Physicians We have studied 35 patients to find the occurrence of hyperchloremic acidosis during the recovery
phase of diabetic ketoacidosis. At admission the patients had typical normochloremic
acidosis, with increased anion gap exactly balancing decreased serum bicarbonate. In ... Cited by 55 - Related articles - All 2 versions
HJ Adrogue, H Wilson, AE Boyd, WN Suki, G … - New England Journal …, 1982 - content.nejm.org In a study of the types of plasma acid-base patterns present at 196 admissions for diabetic ketoacidosis
we found no relation between the initial level of serum total carbon dioxide and the plasma anion
gap; instead, there was a broad spectrum of acid-base patterns, ranging from pure anion- ... Cited by 143 - Related articles - All 3 versions