RH HEISSENBUTTEL, JT BIGGER Jr - Annals of Internal Medicine, 1979 - Am Coll Physicians Bretylium tosylate (Bretylol) has recently been approved for parenteral use against resistant ventricular
arrhythmias. The pharmacologic action of bretylium is complex, and its antiarrhythmic action
differs significantly from other drugs. Bretylium is an adrenergic neuronal blocking agent ... Cited by 52 - Related articles - All 2 versions
J Koch-Weser - The New England journal of medicine, 1979 - ncbi.nlm.nih.gov 1: N Engl J Med. 1979 Mar 1;300(9):473-7. Drug therapy: bretylium. Koch-Weser J.
Publication Types: Review. Mesh Terms: Animals; Bretylium Compounds/therapeutic use*;
Bretylium Tosylate/metabolism; Bretylium Tosylate/pharmacology; ... Cited by 67 - Related articles - All 2 versions
K Chatterjee, WJ Mandel, JK Vyden, WW Parmley, JS … - JAMA, 1973 - Am Med Assoc The cardiac and peripheral vascular effects of bretylium tosylate (adrenergic blocking and antiarrhythmic
agent) administered intravenously in doses of 5 to 10 mg/kg were evaluated in seven patients
with recent myocardial infarction, three with and four without left ventricular failure (LVF). ... Cited by 20 - Related articles - All 2 versions
JE MARKIS, JAN KOCH-WESER - Journal of Pharmacology and Experimental …, 1971 - ASPET ABSTRACT M&axis, JOHN E. ANDJAN KocH-W@: Characteristics and mechanism of inotropic
and chronotropic actions of bretylium tosylate. J. Pharmacol. Exp. Ther. 178: 94-102, 1971.The
inotropic and chronotropic effects ofbretyliumwerestudiedinkittenpapillary muscles and ... Cited by 40 - Related articles - All 2 versions
- ►umich.edu [PDF] JL Anderson, E Patterson, M Conlon, S Pasyk, B … - The American Journal of …, 1980 - Elsevier To determine the kinetics of the antifibrillatory effects of bretylium tosylate and to assess the relative
importance of myocardial versus serum drug concentrations, studies were performed in 32 dogs
after they received bolus injections of bretylium tosylate (6 mg/kg or 2 mg/kg body weight) ... Cited by 73 - Related articles - All 3 versions
- ►ahajournals.org [PDF] DW ROMHILT, SS BLOOMFIELD, RJ LIPICKY, RM … - Circulation, 1972 - Am Heart Assoc RAYMOND J. LIPICKY, MD, RicHiRD M. WELCH, PH.D., ... SUMMARY In a controlled setting
bretylium tosylate was evaluated for efficacy, toxicity, onset, ... 4 mg/kg, and one with 2
mg/kg. Bretylium 4 mg/kg but not 2 mg/kg reduced mean ... PVC frequency by half ... Cited by 26 - Related articles - All 3 versions
T Fujimoto, H Hamamoto, T Peter, A McCullen, N … - American heart …, 1983 - ncbi.nlm.nih.gov Electrophysiologic effects of bretylium were assessed on a recently developed animal model
for analysis of conduction of premature impulses and excitation threshold. Bretylium was administered
intravenously 10 mg/kg over 10 minutes followed by 2 mg/min of infusion immediately ... Cited by 8 - Related articles
JT Bigger Jr, CC Jaffe - The American journal of cardiology, 1971 - ncbi.nlm.nih.gov 1: Am J Cardiol. 1971 Jan;27(1):82-92. The effect of bretylium tosylate on the
electrophysiologic properties of ventricular muscle and Purkinje fibers. Bigger JT Jr,
Jaffe CC. Publication Types: In Vitro. Mesh Terms: Action Potentials ... Cited by 72 - Related articles
AL WIT, C STEINER, AN DAMATO - Journal of Pharmacology and Experimental …, 1970 - ASPET Page 1. THE JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
Copyright (@)1970 by The Williams & Wilkins Co. Vol. 173,No. 2 Printed in USA
ELECTROPHYSIOLOGIC EFFECTS OF BRETYLIUM TOSYLATE ON ... Cited by 48 - Related articles - All 2 versions