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Scholar Results 1 - 10 of about 101 related to HEISSENBUTTEL: New Drugs: Bretylium Tosylate: A Newly Available Antiarrhythmic Drug for Ventricul.... (0.11 sec) 

New Drugs: Bretylium Tosylate: A Newly Available Antiarrhythmic Drug for …


RH HEISSENBUTTEL, JT BIGGER Jr - Annals of Internal Medicine, 1979 - Am Coll Physicians
Bretylium tosylate (Bretylol) has recently been approved for parenteral use against resistant ventricular
arrhythmias. The pharmacologic action of bretylium is complex, and its antiarrhythmic action
differs significantly from other drugs. Bretylium is an adrenergic neuronal blocking agent ...
Cited by 52 - Related articles - All 2 versions

[CITATION] Drug therapy: bretylium.


J Koch-Weser - The New England journal of medicine, 1979 - ncbi.nlm.nih.gov
1: N Engl J Med. 1979 Mar 1;300(9):473-7. Drug therapy: bretylium. Koch-Weser J.
Publication Types: Review. Mesh Terms: Animals; Bretylium Compounds/therapeutic use*;
Bretylium Tosylate/metabolism; Bretylium Tosylate/pharmacology; ...
Cited by 67 - Related articles - All 2 versions

Cardiovascular effects of bretylium tosylate in acute myocardial infarction


K Chatterjee, WJ Mandel, JK Vyden, WW Parmley, JS … - JAMA, 1973 - Am Med Assoc
The cardiac and peripheral vascular effects of bretylium tosylate (adrenergic blocking and antiarrhythmic
agent) administered intravenously in doses of 5 to 10 mg/kg were evaluated in seven patients
with recent myocardial infarction, three with and four without left ventricular failure (LVF). ...
Cited by 20 - Related articles - All 2 versions

Characteristics and mechanism of inotropic and chronotropic actions of bretylium …


JE MARKIS, JAN KOCH-WESER - Journal of Pharmacology and Experimental …, 1971 - ASPET
ABSTRACT M&axis, JOHN E. ANDJAN KocH-W@: Characteristics and mechanism of inotropic
and chronotropic actions of bretylium tosylate. J. Pharmacol. Exp. Ther. 178: 94-102, 1971.The
inotropic and chronotropic effects ofbretyliumwerestudiedinkittenpapillary muscles and ...
Cited by 40 - Related articles - All 2 versions

Kinetics of antifibrillatory effects of bretylium: correlation with myocardial drug …

- umich.edu [PDF] 
JL Anderson, E Patterson, M Conlon, S Pasyk, B … - The American Journal of …, 1980 - Elsevier
To determine the kinetics of the antifibrillatory effects of bretylium tosylate and to assess the relative
importance of myocardial versus serum drug concentrations, studies were performed in 32 dogs
after they received bolus injections of bretylium tosylate (6 mg/kg or 2 mg/kg body weight) ...
Cited by 73 - Related articles - All 3 versions

Experience with bretylium tosylate by a hospital cardiac arrest team

- ahajournals.org [PDF] 
DA Holder, AD Sniderman, G Fraser, EL Fallen - Circulation, 1977 - Am Heart Assoc
8. Greenblatt DJ, Duhme DW, Koch-Weser J, Smith TW: Intravenous digoxin on a bioavailability
standard: Slow infusion and rapid injection. Clin Pharmacol Ther 15: 510, 1974 9. Preibisz
JJ, Butler VP Jr, Lindenbaum J: Digoxin tablet bioavailability: Single-dose and ...
Cited by 48 - Related articles - All 3 versions

Evaluation of bretylium tosylate for the treatment of premature ventricular …

- ahajournals.org [PDF] 
DW ROMHILT, SS BLOOMFIELD, RJ LIPICKY, RM … - Circulation, 1972 - Am Heart Assoc
RAYMOND J. LIPICKY, MD, RicHiRD M. WELCH, PH.D., ... SUMMARY In a controlled setting
bretylium tosylate was evaluated for efficacy, toxicity, onset, ... 4 mg/kg, and one with 2
mg/kg. Bretylium 4 mg/kg but not 2 mg/kg reduced mean ... PVC frequency by half ...
Cited by 26 - Related articles - All 3 versions

Electrophysiologic effects of bretylium on canine ventricular muscle during acute …


T Fujimoto, H Hamamoto, T Peter, A McCullen, N … - American heart …, 1983 - ncbi.nlm.nih.gov
Electrophysiologic effects of bretylium were assessed on a recently developed animal model
for analysis of conduction of premature impulses and excitation threshold. Bretylium was administered
intravenously 10 mg/kg over 10 minutes followed by 2 mg/min of infusion immediately ...
Cited by 8 - Related articles

[CITATION] The effect of bretylium tosylate on the electrophysiologic properties of ventricular …


JT Bigger Jr, CC Jaffe - The American journal of cardiology, 1971 - ncbi.nlm.nih.gov
1: Am J Cardiol. 1971 Jan;27(1):82-92. The effect of bretylium tosylate on the
electrophysiologic properties of ventricular muscle and Purkinje fibers. Bigger JT Jr,
Jaffe CC. Publication Types: In Vitro. Mesh Terms: Action Potentials ...
Cited by 72 - Related articles

Electrophysiologic effects of bretylium tosylate on single fibers of the canine …


AL WIT, C STEINER, AN DAMATO - Journal of Pharmacology and Experimental …, 1970 - ASPET
Page 1. THE JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
Copyright (@)1970 by The Williams & Wilkins Co. Vol. 173,No. 2 Printed in USA
ELECTROPHYSIOLOGIC EFFECTS OF BRETYLIUM TOSYLATE ON ...
Cited by 48 - Related articles - All 2 versions


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