BS MITCHELL, WN KELLEY - Annals of Internal Medicine, 1980 - Am Coll Physicians Deficiencies of two enzymes that catalyze sequential reactions in the purine
catabolic pathway have been causally associated with immunodeficiency states.
Adenosine deaminase (ADA) deficiency results in severe combined ... Cited by 48 - Related articles - All 2 versions
RM Fox, RF Kefford, EH Tripp, IW Taylor - Cancer Res, 1981 - AACR ABSTRACT Cultured human T-cell leukemic lymphocytes have enhanced sensitivity to
growth inhibition by deoxyadenosine. ... INTRODUCTION The introduction of drugs
inhibiting ADA,2 in particular deox- ycoformycin, which is currently under ... Cited by 42 - Related articles - All 3 versions
EW Gelfand, JJ Lee, HM Dosch - Proc Natl Acad Sci USA, 1979 - National Acad Sciences Page 1. Proc. Natl. Acad. Sci. USA Vol. 76, No. 4, pp. 1998-2002, April 1979
Immunology Selective toxicity of purine deoxynucleosides ... Cited by 67 - Related articles - All 7 versions
- ►pnas.org [PDF] DA Carson, DB Wasson, E Lakow, N … - Proceedings of the National Academy of Sciences, 1982 - National Acad Sciences Page 1. Proc. Nati Acad. Sci. USA Vol. 79, pp. 3848-3852, June 1982 Medical Sciences
Possible metabolic basis for the different immunodeficient ... Cited by 58 - Related articles - All 7 versions
- ►aacrjournals.org [PDF] RF Kefford, MA Helmer, RM Fox - Cancer Research, 1982 - AACR Page 1. [CANCER RESEARCH 42, 3822-3827, September 1982] 0008-5472/82/0042-OOOOS02.
00 S-Adenosylhomocysteine Hydrolase Inhibition in Deoxyadenosine-treated ... Cited by 14 - Related articles - All 2 versions
J Uberti, JJ Lightbody, RM Johnson - The Journal of Immunology, 1979 - Am Assoc Immnol Micromolar deoxyadenosine inhibits leucine uptake during the 1st day of
proliferation in mitogen-stimulated lymphocytes if adenosine deaminase is
inhibited. This inhibition occurs before DNA synthesis begins, suggest- ing ... Cited by 29 - Related articles - All 2 versions
DA Carson, J Kaye, S Matsumoto, JE … - Proc. nat. Acad. Sci. USA, 1979 - National Acad Sciences ABSTRACT Human malignant T cell lines have high levels of deoxyribonucleoside
phosphorylating activity and low levels of deoxyribonucleotide dephosphorylating
activity. When in- cubated with deoxyadenosine or thymidine, the malignant ... Cited by 135 - Related articles - All 7 versions
[CITATION] Selective treatment of lymphoid malignancy with adenosine deaminase inhibitors
CA Koller, BS Mitchell, MR Grever, E Mejias, … - Cancer treatment reports - ncbi.nlm.nih.gov 1: Cancer Treat Rep. 1979 Nov-Dec;63(11-12):1949-52. Treatment of acute
lymphoblastic leukemia with 2'-deoxycoformycin: clinical ... Cited by 42 - Related articles
