EJ SCHAEFER, LA ZECH, DE SCHWARTZ, … - Annals of Internal …, 1980 - Am Coll Physicians High-density (HD) lipoprotein cholesterol levels have been inversely associated with the incidence
of coronary heart disease. The clinical features were reviewed and the prevalence of clinically
evident coronary artery or other vascular disease was ascertained in 27 homozygous and ... Cited by 130 - Related articles - All 2 versions
DS FREDRICKSON, PH ALTROCCHI, LV … - Annals of Internal …, 1961 - Am Coll Physicians Dr. Donald S. Fredrickson: This is the story of an island, a family, and a strange malady. In telling
it we hope to acquaint you with some of the biochemical approaches to current problems in both
fat transport and the lipid storage diseases. Since our story lends itself to the narrative ... Cited by 178 - Related articles - All 2 versions
C Serfaty-Lacrosniere, F Civeira, A Lanzberg, P Isaia, J … - Atherosclerosis, 1994 - Elsevier Decreased levels of plasma high density lipoprotein (HDL) cholesterol have been associated
with premature cardiovascular disease (CVD). Tangier disease is an autosomal co-dominant
disorder in which homozygotes have a marked deficiency of HDL cholesterol and ... Cited by 159 - Related articles - All 4 versions
- ►ahajournals.org [PDF] EJ Schaefer, WH Heaton, MG Wetzel, HB … - … , and Vascular Biology, 1982 - Am Heart Assoc Human lymph chylomicrons contain significant quantities of apo Al and A-ll, which can serve
as precursors for these constituents within plasma HDL. 42 This conversion process appears
to be defective in Tangier homozygotes, 43 resulting in rapid and altered apo Al and A-ll ... Cited by 136 - Related articles - All 3 versions
[CITATION] Brewer (Jr), HB. Coronary heart disease prevalence and other clinical features in …
- ►jlr.org [PDF] EJ Schaefer, DW Anderson, LA Zech, FT Lindgren, … - The Journal of Lipid …, 1981 - ASBMB Molecular Disease Branch, National Heart, Lung, and Blood Institute, National Institutes of
Health, Bethesda, MD 20205 and the Donner Laboratory, Lawrence Berkeley Laboratory, University
of California, Berkeley, CA3 ... Abstract The metabolism of apolipoproteins AI and A-11, ... Cited by 45 - Related articles - All 3 versions
LL Kay, R Ronan, EJ Schaefer, HB … - Proc. Natd Acad. Sci. …, 1982 - National Acad Sciences Page 1. Proc. Natd Acad. Sci. USA Vol. 79, pp. 2485-2489, April 1982 Biochemistry Tangier
disease: A structural defect in apolipoprotein AI (apoA-ITangir) (apolipoprotein
A-1H/dyslipoproteinemia/atherosclerosis/high density lipoproteins/cholesterol) ... Cited by 37 - Related articles - All 7 versions
- ►nih.gov [PDF] DS Fredrickson - Journal of Clinical Investigation, 1964 - pubmedcentral.nih.gov A familial syndrome consisting of complete or nearly complete absence of plasma high density
lipoprotein (HDL) associated with storage of cholesterol esters in reticuloendothelial tissues
has been previously reported (1, 2). It has been given the name Tangier disease after the ... Cited by 84 - Related articles - All 5 versions
EJ Schaefer, CB Blum, RI Levy, LL Jenkins, P … - New England Journal …, 1978 - content.nejm.org To define the metabolic defect in Tangier disease, we studied the kinetics of [125I]-high-density
lipoprotein apolipoproteins (apolipoproteins AI and A-II) in 11 normal subjects, two obligate
heterozygotes, and two homozygotes. Mean synthesis of apolipoproteins A-1 and A-11 ... Cited by 115 - Related articles - All 2 versions
PN Herbert, T Forte, RJ Heinen, DS … - New England Journal of …, 1978 - content.nejm.org Normal high-density lipoproteins are absent from plasma in Tangier disease, and the disorder
is characterized by accumulation of cholesteryl esters in several tissues, particularly those of
the reticuloendothelial system. Electron microscopy of the abnormal high-density ... Cited by 29 - Related articles - All 2 versions
