… , JE GADEK, JD FULMER, BR LINE - Annals of Internal …, 1981 - Am Coll Physicians The alveolitis of pulmonary sarcoidosis is characterized by an intense, mononuclear cell infiltrate
that probably precedes granuloma formation. Pathogenic mechanisms underlying pulmonary sarcoidosis
can be shown by study of the ... Cited by 208 - Related articles
GW Hunninghake, JE Gadek, RC Young, O … - New England Journal …, 1980 - content.nejm.org Pulmonary granulomata of sarcoidosis are composed primarily of mononuclear phagocytic cells that are
probably derived from blood monocytes. To evaluate the concept that recruitment of blood monocytes
to the sarcoid lung is mediated by ... Cited by 134 - Related articles - All 2 versions
GW Hunninghake, RG Crystal - New England Journal of Medicine, 1981 - content.nejm.org Using the monoclonal antibodies OKT4 and OKT8, we determined the proportions of helper and
suppressor T cells in patients with sarcoidosis and high-intensity alveolitis, patients with
sarcoidosis and low-intensity ... Cited by 471 - Related articles - All 2 versions
BA Keogh, GW Hunninghake, BR Line, RG Crystal - Name: Am. Rev. Respir. …, 1983 - osti.gov The Energy Citations Database (ECD) provides access to historical and current research (1948 to
the present) from the Department of Energy (DOE) and predecessor agencies.
Cited by 148 - Related articles - Cached - All 3 versions
P Pinkston, PB Bitterman, RG Crystal - New England Journal of …, 1983 - content.nejm.org We investigated the possible role of interleukin-2, a T-cell product that stimulates the clonal
increase of responsive T lymphocytes, in the pathogenesis of pulmonary sarcoidosis. We obtained
mononuclear effector cells from the ... Cited by 224 - Related articles - All 5 versions
RP DANIELE, JH DAUBER, MD … - Annals of Internal …, 1980 - Am Coll Physicians Patients with active sarcoidosis (acute and chronic) have a depression in systemic cell-mediated
immunity manifested by a reduction in the number of circulating T cells and impaired responses of
these cells to polyclonal mitogens ... Cited by 158 - Related articles - All 2 versions
GW Hunninghake, JD Fulmer, RC Young Jr, … - The American review of …, 1979 - ncbi.nlm.nih.gov Pulmonary sarcoidosis is an interstitial disease characterized by granulomas within the lung
parenchyma, anergy to a variety of skin tests, and decreased numbers of circulating T-lymphocytes.
To evaluate the effector cell ... Cited by 95 - Related articles
- ►nih.gov [PDF] GW Hunninghake, RG Crystal - Journal of Clinical Investigation, 1981 - pubmedcentral.nih.gov A B STR A CT Pulmonary sarcoidosis is a disorder in which local granuloma formation is perpetuated
by acti- vated lung T lymphocytes. The present study suggests that lung T lymphocytes may also play
a critical role in modulating local ... Cited by 87 - Related articles - All 4 versions
BR Line, GW Hunninghake, BA Keogh, AE Jones, GS … - Am Rev Respir Dis, 1981 - osti.gov Current concepts of the pathogenesis of sarcoidosis suggest that the alveolitis of this disorder is
related to increased numbers of mononuclear phagocytes and activated T-lymphocytes within the
lung.^To determine if 67Ga ... Cited by 111 - Related articles - Cached - All 3 versions
GW Hunninghake - The American review of respiratory disease, 1984 - cat.inist.fr Release of interleukin-1 by alveolar macrophages of patients with active pulmonary
sarcoidosis. GW HUNNINGHAKE The American review of respiratory disease 129:44, 569-572,
American Lung Association, 1984. Dans la sarcoïdose pulmonaire: 1) les ... Cited by 145 - Related articles - All 2 versions
