P Questions, P Internist - Annals of Internal Medicine - Am Coll Physicians W hat should the busy internist do when his or her patient, while taking several medications,
suddenly develops a new clinical problem, such as hepatitis? Is the acute hepatitis drug
related? If so, which drug is to blame? The case report by May and colleagues in this ... Related articles
KA Prendergast, CL Berg, R … - Annals of Internal Medicine, 2000 - Am Coll Physicians Letters commenting on an Annals article will be considered if they are received within 6 weeks
of the time the article was published. Only some of the letters received can be published. Published
letters are edited and may be shortened; tables and figures are included only selectively. ... Cited by 8 - Related articles - BL Direct - All 3 versions
T Schiano, K Dolehide, J Hart, AL Baker - Digestive diseases and sciences, 2000 - Springer Troglitazone (Rezulin), a recently introduced oral antidiabetic drug of the thiazolidinedione
class, is ordinarily prescribed along with sulfonylureas or in- sulin to improve blood sugar
control. Troglitazone and other thiazolidinedione derivatives appear to bind to a nuclear ... Cited by 9 - Related articles - BL Direct - All 5 versions
D Nieremberg, K Melmon - Melmon and Morrelli's Clinical …, 2000 - books.google.com INTRODUCTION TO CLINICAL PHARMACOLOGY AND RATIONAL THERAPEUTICS David
W. Nierenberg, Kenneth L. Melmon Chapter Outline HISTORICAL PERSPECTIVE ON CURRENT
PROBLEMS WITH THERAPEUTICS AN APPROACH TO RATIONAL THERAPEUTICS AN ... Cited by 3 - Related articles - All 2 versions
WL Isley - eds, 2003 - informahealthcare.com Thiazolidinediones are insulin sensitisers now widely used for the treatment of Type 2 diabetes
mellitus. The initial marketed drug in this class, troglitazone, was removed from the market worldwide
after approximately 3 years of use due to rare but severe hepatotoxicity, which sometimes ... Cited by 53 - Related articles - BL Direct - All 9 versions
H Li, DS Heller, CB Leevy, KG Zierer, KM Klein - Journal of diabetes and its …, 2000 - Elsevier A 71-year-old man with type 2 diabetes was treated with troglitazone for 10 months. He had been
initially treated by his private physician. He was started on oral troglitazone, 200 mg daily in August
of 1998. Laboratory studies performed in October of 1998 showed normal liver function ... Cited by 11 - Related articles - BL Direct - All 10 versions
- ►annals.org [PDF] LD May, JH Lefkowitch, MT Kram, DE … - Annals of internal …, 2002 - Am Coll Physicians Louis D. May, MD; Jay H. Lefkowitch, MD; Michael T. Kram, MD; and David E. Rubin, MD ...
Background: Pioglitazone is an oral hypoglycemic agent in the thiazolidinedione class. Only
one case of hepatotoxicity related to this agent has previously been reported. Objective: ... Cited by 86 - Related articles - All 6 versions
S Jagannath, R Rai - Annals of internal medicine, 2000 - ncbi.nlm.nih.gov 1: Ann Intern Med. 2000 Apr 18;132(8):677. Comment on: Ann Intern Med. 1998 Jul
1;129(1):36-8. Ann Intern Med. 1998 Jul 1;129(1):38-41. Rapid-onset subfulminant
liver failure associated with troglitazone. Jagannath S, Rai R. ... Cited by 12 - Related articles - BL Direct
TR Marcy, ML Britton, SM Blevins - The Annals of …, 2004 - Harvey Whitney Books CASE SUMMARY: A 39-year-old black woman with type 2 diabetes mellitus, hypertension, and
congestive heart failure presented to a pharmacist-staffed diabetes comanagement service. She
reported fatigue, dark brown urine, nausea, itching, and loss of appetite. Pioglitazone was ... Cited by 43 - Related articles - All 5 versions
AA Alsheikh-Ali, HM Abourjaily, RH Karas - The American journal of cardiology, 2002 - Elsevier A database describing all reports of adverse drug reactions from November 1997 to April
2000, in which either of the 2 most widely prescribed statins, simvastatin or atorvastatin, were
listed as the primary or secondary causal suspect, was obtained from the FDA by a ... Cited by 17 - Related articles - All 5 versions
