DA Ausiello, DJ Benos, F Abboud, W Koopman, P … - Ann Intern Med, 2004 - Am Coll Physicians Pain is a multidimensional sensory experience that is intrinsically unpleasant and associated
with hurting and soreness. It may vary in intensity (mild, moderate, or severe), quality (sharp,
burning, or dull), duration (tran- sient, intermittent, or persistent), and referral (superficial ... Cited by 200 - Related articles - BL Direct - All 17 versions
CJ Woolf - Life sciences, 2004 - Elsevier Peripheral neuropathic pain, that clinical pain syndrome associated with lesions to the peripheral
nervous system, is characterized by positive and negative symptoms. Positive symptoms include
spontaneous pain, paresthesia and dysthesia, as well as a pain evoked by normally ... Cited by 111 - Related articles - All 4 versions
DE Anderson - wvc.omnibooksonline.com GENERAL KEY POINTS Rational treatment of pain requires an appreciation of its
consequences, a fundamental understanding of the mechanisms which are responsible for its
production and a practical appreciation of the analgesic drugs that are available. The ... Related articles - View as HTML
J Scholz, CJ Woolf - nature neuroscience, 2002 - unc.edu Pain can be an adaptive sensation, an early warning to protect the body from tissue injury. By
the introduction of hypersensitivity to normally innocuous stimuli, pain may also aid in repair
after tissue damage. Pain can also be maladaptive, reflecting pathological function of the ... Cited by 315 - Related articles - BL Direct - All 12 versions
PV Rasmussen, SH Sindrup, TS Jensen, FW Bach - Pain, 2004 - Elsevier The study sought to determine if symptoms and signs cluster differentially in groups of patients
with increasing evidence of neuropathic pain (NP). We prospectively looked at symptoms and
signs in 214 patients with suspected chronic NP of moderate to severe intensity. ... Cited by 102 - Related articles - All 18 versions
CJ Woolf - wellcome.ac.uk Normally, pain is produced only by intense stimuli that are potentially or actually damaging to
tissue (technically known as noxious stimuli, although commonly referred to as pain stimuli).
This pain is mediated by a specific system of high-threshold peripheral and central ... Related articles - Cached
TS Jensen, R Baron - Pain, 2003 - Elsevier For centuries, clinicians have been taught to examine and classify patients on the basis of topographical
lesion and the underlying pathology. In most clinical specialities, such an approach has been
a key element in understanding the pathophysiology of diseases and has led to progress ... Cited by 172 - Related articles - BL Direct - All 7 versions
- ►jneurosci.org KA Moore, T Kohno, LA Karchewski, J Scholz, … - Journal of …, 2002 - Soc Neuroscience To clarify whether inhibitory transmission in the superficial dorsal horn of the spinal cord is reduced
after peripheral nerve injury, we have studied synaptic transmission in lamina II neurons of an
isolated adult rat spinal cord slice preparation after complete sciatic nerve transection ... Cited by 236 - Related articles - BL Direct - All 8 versions
- ►yale.edu [PDF] RR Ji, T Kohno, KA Moore, CJ Woolf - TRENDS in Neurosciences, 2003 - Elsevier Synaptic plasticity is fundamental to many neurobiological functions, including memory and
pain. Central sensitization refers to the increased synaptic efficacy established in somatosensory
neurons in the dorsal horn of the spinal cord following intense peripheral noxious stimuli, ... Cited by 385 - Related articles - All 9 versions
DE Anderson, WW Muir - Veterinary Clinics of North America: Food Animal …, 2005 - Elsevier Pain and the biologic responses to it are part of a highly integrated multidimensional system
that causes all animals to react, respond (fight, flight, freeze), and protect themselves from their
environment. Whether or not animals “feel” pain the same as humans is immaterial, and ... Cited by 11 - Related articles - All 3 versions
