Authors
Mahmood Akbarian, Seyedeh Tahereh Faezi, Farhad Gharibdoost, Farhad Shahram, Abdolhadi Nadji, Ahmad Reza Jamshidi, Maasoumeh Akhlaghi, Nahid Shafaie, Maryam Akhlaghkhah, Fereydoun Davatchi
Publication date
2010/10
Journal
International journal of rheumatic diseases
Volume
13
Issue
4
Pages
374-379
Publisher
Blackwell Publishing Ltd
Description
Objective: Systemic lupus erythematosus (SLE) as a chronic autoimmune disease has a worldwide distribution. There is a wide variation in the natural history of SLE among different ethnic and geographic groups. The aim of this study was to show the manifestations of SLE in Iranian patients.
Methods: The study was on manifestations of SLE according to the database of the Rheumatology Research Center (RRC), Tehran, Iran, on registered patients during the period of 1976 to 2009.
Results: A total of 2280 SLE patients (2052 female and 228 male) were studied. The female : male ratio was 9 : 1 and the mean age at presentation was 24.4 ± 10.4 years. Prevalence of manifestations included: musculoskeletal (83.2%), cutaneous (81.1%), renal (65.4%), neuropsychiatric (23.4%), pulmonary (21.5%), cardiac (17.2%), and hematologic (66.4%) symptoms. There was positive antinuclear antibodies in 86.4 …
Scholar articles
M Akbarian, ST Faezi, F Gharibdoost, F Shahram… - International journal of rheumatic diseases, 2010