Authors
M Karimifar, F Gharibdoost, M Akbarian, AP Meysamie, Sh Khosravi, Mozh Karimifar, F Shahram, A Nadji, AR Jamshidi, M Akhlaghi, B Yazdani, F Davatchi
Publication date
2007/9
Journal
APLAR Journal of Rheumatology
Volume
10
Issue
3
Pages
221-226
Publisher
Blackwell Publishing Asia
Description
Objective: There are some clues that measurement of triglyceride (TG) and high‐density lipoprotein (HDL) and their correlation with tumor necrosis factor alpha (TNF‐α), soluble TNF‐α receptor type 1 and type 2 (sTNFR1, sTNFR2) in serum could be valuable in the assessment of disease activity of systemic lupus erythematosus (SLE) patients.
Methods: In this cross‐sectional study, fasting blood samples were obtained from 86 SLE patients referred to the Rheumatology Research Center of Tehran University in Shariati Hospital, Iran. Disease activity was determined by using the Systemic Lupus Erythematosus Disease Activity Index (SLEDAI). TG and HDL obtained after overnight fasting were analysed by routine chemistry. Levels of circulating TNF‐α, sTNFR1, and sTNFR2 were determined by enzyme‐linked immunosorbent assay.
Results: Triglyceride levels were associated with SLEDAI (r = 0.59, P < 0.001 …
Scholar articles
M Karimifar, F Gharibdoost, M Akbarian, AP Meysamie… - APLAR Journal of Rheumatology, 2007