View article

Osteoporosis is a metabolic disease that causes bones density decrease and making them more likely to break or deformation. Osteoporosis is a silent and very common disease. In according to the WHO report, in 1991 osteoporosis threat the health of human after strokes and cancer. 70% of the Iranian female population and 50% of male by 50 years-old and over experience osteoporosis in their lifetime too. So far some studies and researches have been done about the diagnostic and treatment of this disease including selective diet and medicines. In this study we decided to determine the plasma antioxidants level in relation to the bone density in Iranian female population. This study had been done on 140 patients in Tehran Jami Clinic. The amount of plasma antioxidant activity was determined and by FRAP assay. The results were compared between patient and control group. The average of plasma antioxidant activity in control and patient group (Total, Mild, Severe) were 851.62±315.68; 923.08±256.84; micro molar, respectively. The results of this study showed that the plasma antioxidants activity in osteoporotic patients is more than control group, although this difference is not meaningful (p= 0.2). Also the correlation between plasma antioxidants activity and femoral T-score in all of the groups showed inverted relationship. This relation in all of the groups is meaning full (p= 0.051).