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How to care for the patients has a principle role in the quality of the services provided, so patients' management is one of the major duties of doctors. However, in Iran there is not a comprehensive program to achieve this goal and medical training is based on diseases while it should be patient based. This study tries to provide a practical approach in training how to manage patients. In this research 60 general practitioners working in urban health centers in Isfahan were randomly selected and studied. 30 physicians from health center number 1 were put in case group and the other 30 from health center number 2 were placed in control group. In conducting the project 4 physicians who had received necessary training worked as instructors. In the beginning of the study, the case group attended in theory classes about integrated patient management, and at the end of this class a package of integrated patient management was given to them. Then the plan was performed practically in the field. Throughout the study both case and control group received the usual training of health centers. The performance of the physicians was evaluated through check list both in the beginning and end of the study. Before the study the mean scores of physicians' performance in both groups was the same; however, after the intervention the mean score of the case group was significantly higher than that of the control group. In the end of the study the mean score of clinical performance in case group was 48.9 and in control group was 42.1 (P< 0.05), mean score of management performance in case group was 38.6 and in …