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Behçet’s Disease (BD) is classified among vasculitides. There are actually two nationwide surveys of BD; Iran (3153 patients) and Japan (3316 patients). There are 4 major case series in the world, Turkey (2147 patients), Korea (1155 patients), Morocco (673 patients), and England (419 patients). Other series are based on less than 200 patients. Mucous Membrane Manifestations: Oral aphthosis was seen in 96.4% of patients in Iran, 98.2% in Japan, 100% in Turkey, 97.5% in Korea, 100% in Morocco, and 100% in England. Genital aphthosis is seen less frequently. It was detected in 64.8% in Iran, 73.2% in Japan, 88.2% in Turkey, 56.7% in Korea, 83.5% in Morocco, and 89% in England.

Skin Manifestations: They were seen in 71.8% of patients in Iran, 87.1% in Japan, 60.6% in Korea, and 86% in England. Behçet’s Pustulosis or pseudo-folliculitis was seen in 63.7% of patients in Iran. Skin aphthosis is not frequent but it is the most characteristic lesion of BD. Subcutaneous Lesions: Erythema nodosum is seen in 22.6% of patients in Iran. They are seen more frequently in China and Korea, around 55% of patients.