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The etiology of Behçet’s disease (BD) is still unknown but it follows the general pattern of autoimmune disorders. Both environmental and genetic factors contribute to its pathogenesis¹. Although the genetic susceptibility seems to be multifactorial, the most important association is with the class I histocompatibility gene B52. HLA-B51, a split antigen of HLA-B5, has generally been associated with BD in different countries notably those along the silk route3.