Authors
Hamideh Aghaei, Shayan Mostafaei, Saeed Aslani, Ahmadreza Jamshidi, Mahdi Mahmoudi
Publication date
2019/12
Journal
BMC medical genetics
Volume
20
Pages
1-10
Publisher
BioMed Central
Description
Background
Currently published studies investigating association between the killer cell immunoglobulin-like receptor (KIR) gene polymorphisms and rheumatoid arthritis (RA) reported inconsistent and contradictory results. Hence, we aim to carry out this comprehensive meta-analysis of all eligible studies meeting the inclusion criteria to achieve precise and comprehensive relationships between genetic variations in KIR gene cluster and risk of RA.
Methods
Databases of Medline/PubMed and Scopus were searched to investigate case-control studies prior to May 2018. The associations between KIR gene polymorphisms and RA susceptibility were analyzed by computing the odds ratio (OR) and 95% confidence interval (95% CI) for each study.
Results
A total of 11 comparative case-control studies involving 1847 RA …
Total citations
Scholar articles
H Aghaei, S Mostafaei, S Aslani, A Jamshidi… - BMC medical genetics, 2019