Authors
Hua Zhu, Lijun Zuo, Wanlin Zhu, Jing Jing, Zhe Zhang, Lingling Ding, Fengjuan Wang, Jian Cheng, Zhenzhou Wu, Yongjun Wang, Tao Liu, Zixiao Li
Publication date
2022/10
Journal
Brain Imaging and Behavior
Volume
16
Issue
5
Pages
2199-2219
Publisher
Springer US
Description
Stroke induced by basal ganglia infarction often impair cognitive function. The exploration of topological patterns in structural and functional networks associated cognitive impairment after stroke may contribute to understand the pathological mechanism of cognitive impairment caused by stroke. In this paper, graph theory analysis was applied to diffusion-weighted imaging (DWI) data and resting-state functional MRI (fMRI) data from 23 post-stroke patients with cognitive impairment (PSCI), 17 post-stroke patients without cognitive impairment (NPSCI), and 29 healthy controls (HC). Structural and functional connectivity between 90 cortical and subcortical brain regions was estimated and set threshold to construct a set of undirected graphs. Network-based statistics (NBS) was used to characterize altered connectivity patterns among the three groups. Compared to HC, the PSCI group demonstrated substantial …
Total citations
2022202315
Scholar articles