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In spite of many epidemiologic studies, there is still insufficient evidence on the effects of daily physical activity on osteoarthritis. The purpose of this study was to evaluate the association between squatting, climbing, kneeling, lifting and carrying weights and knee osteoarthritis.

This population‐based case control study was the second stage of the World Health Organization – Community Oriented Program for Control of Rheumatic Diseases (WHO‐COPCORD), in which 263 cases and 263 controls aged 30–70 years were selected from 780 eligible cases and 4373 eligible controls identified in the first‐stage survey in Tehran. Demographic and lifestyle data were obtained from all the participants. The selection probability of each case and control and the stabilized weight was estimated using the restricted cubic spline models. Multivariable regression models by inverse probability weighting were used …