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Behçet’s disease is relatively a young disease, described in 1937. Nevertheless, it has already 17 sets of diagnosis/classification criteria. The first set was created in 1946 and the last in 2010. The first created by an international collaboration was the International Study Group criteria (ISG) in 1990 with the collaboration of 7 countries, and the last the International Criteria for Behçet’s Disease (ICBD) in 2010 with the collaboration of 27 countries. In ICBD, the following signs get each 2 points: oral aphthosis, genital aphthosis, and ocular manifestations. Skin manifestations, vascular lesions, neurologic manifestations, and a positive pathergy test get each 1 point. To classify or diagnose a patient as Behçet’s disease, the patient must totalize 4 or more points. As pathergy test is not performed in some countries, mainly western countries, its use is facultative. However, in patients not fulfilling the ICBD it is …