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To independently replicate the top findings from 4 published genome‐wide association studies (GWAS) of susceptibility genes in Behçet's disease (BD).

We tested 14 single‐nucleotide polymorphisms (SNPs) in 13 genomic loci (excluding the major histocompatibility complex [MHC], IL10, and IL23R–IL12RB2, which have already been associated with BD in Iranians) for allelic and genotypic associations with BD in 973 patients and 828 controls from Iran and performed meta‐analyses of the significantly associated markers.

Six SNPs (in decreasing order of significance, rs7616215 located 38 kb downstream of CCR1, rs2617170 [p.Asn104Ser] in KLRC4, rs17810546 in IL12A–AS1, rs7574070 in STAT4, and rs10050860 [p.Asp575Asn] and rs13154629 in ERAP1) were nominally associated with BD in both allelic association tests (5.05 × 10⁻⁹ ≤ P_allele ≤ 7.55 × 10⁻³) and sex …