Authors
Ramazan Rezaei, Shayan Mostafaei, Saeed Aslani, Ahmadreza Jamshidi, Mahdi Mahmoudi
Publication date
2018/10
Source
International journal of rheumatic diseases
Volume
21
Issue
10
Pages
1746-1755
Description
Background
Several genetic studies have assessed the association between polymorphisms in killer immunoglobulin‐like receptors (KIR) genes and susceptibility of individuals to ankylosing spondylitis (AS), but the findings have been inconclusive and incongruous. Therefore, we conducted this meta‐analysis of all case‐control studies meeting the inclusion criteria for obtaining an exact conclusion of the effect of KIR polymorphisms on the risk of AS.
Methods
A systematic literature search was conducted in electronic databases, including Scopus web of science, ScienceDirect, and PubMed to find all eligible studies exploring the association between KIR polymorphisms and the risk of AS, prior to June 2017. Pooled odds ratios (OR) and their corresponding 95% CIs were used to evaluate the strength of the association between KIR polymorphisms and the risk of AS.
Results
A total of 16 case‐control studies …
Total citations
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