Authors
Abbas Shahi, Saeed Aslani, MohammadReza Ataollahi, Mahdi Mahmoudi
Publication date
2019/8/1
Source
Inflammopharmacology
Volume
27
Pages
649-661
Publisher
Springer International Publishing
Description
Magnesium deficiency (MgD) can cause inflammation in human body. The known mechanisms of inflammation caused by MgD include activation of phagocytic cells, opening of calcium channels, activation of the N-methyl-d-aspartate (NMDA) receptor, and activation of nuclear factor (NF)-κB. In addition, MgD causes systemic stress response through neuroendocrinological pathways. The inflammation caused by MgD can result in pro-atherogenic changes in the metabolism of lipoproteins, endothelial dysfunction, and high blood pressure. Studies suggest that magnesium may play an important role in the pathophysiology of some inflammatory diseases. Several clinical trials and laboratory studies have been done on the functional role of magnesium. In this study, we review some inflammatory diseases, in which the magnesium has a role in their pathophysiology. Among these diseases, diabetes, asthma …
Total citations
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Scholar articles
A Shahi, S Aslani, MR Ataollahi, M Mahmoudi - Inflammopharmacology, 2019