Authors
Mohsen Moghoofei, Shayan Mostafaei, Amir Ashraf-Ganjouei, Hoda Kavosi, Mahdi Mahmoudi
Publication date
2018/1/1
Source
Microbial pathogenesis
Volume
114
Pages
436-443
Publisher
Academic Press
Description
Background
Hepatitis B is one of the most common infectious diseases worldwide. In patients undergoing immunosuppressive therapy such as rheumatic diseases, reactivation of hepatitis B virus (HBV) is considered clinically important. This systematic review and meta-analysis were performed to determine the prevalence rate of HBV reactivation in rheumatic patients from different parts of the world.
Methods
The authors performed a systematic literature review from several reliable databases including Scopus, ISI Web of Science and PubMed. Furthermore, the keywords of this research were “Hepatitis B virus”, “Rheumatic diseases”, “HBV reactivation”, “Anti-TNF”, “DMARDs” and “Biologic agents”.
Results
The authors selected 30 studies out of 983 for the present review. The overall estimation of the prevalence of HBV reactivation was 1.4 (95% confidence interval (CI): 1.3–1.6). Also, the heterogeneity in estimating …
Scholar articles
M Moghoofei, S Mostafaei, A Ashraf-Ganjouei… - Microbial pathogenesis, 2018