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David J Duffy
David J Duffy
Verified email at whitney.ufl.edu
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Cited by
Year
Problems, challenges and promises: perspectives on precision medicine
DJ Duffy
Briefings in bioinformatics 17 (3), 494-504, 2016
1162016
Wnt signaling promotes oral but suppresses aboral structures in Hydractinia metamorphosis and regeneration
DJ Duffy, G Plickert, T Kuenzel, W Tilmann, U Frank
Development 137 (18), 3057-3066, 2010
862010
Integrative Genome-Scale Analysis Identifies Epigenetic Mechanisms of Transcriptional Deregulation in Unfavorable NeuroblastomasEpigenetic Alterations in Unfavorable Neuroblastomas
KO Henrich, S Bender, M Saadati, D Dreidax, M Gartlgruber, C Shao, ...
Cancer research 76 (18), 5523-5537, 2016
772016
Induced stem cell neoplasia in a cnidarian by ectopic expression of a POU domain transcription factor
RC Millane, J Kanska, DJ Duffy, C Seoighe, S Cunningham, G Plickert, ...
Development 138 (12), 2429-2439, 2011
752011
GSK3 Inhibitors Regulate MYCN mRNA Levels and Reduce Neuroblastoma Cell Viability through Multiple Mechanisms, Including p53 and Wnt Signaling
DJ Duffy, A Krstic, T Schwarzl, DG Higgins, W Kolch
Molecular cancer therapeutics 13 (2), 454-467, 2014
742014
Sea turtle fibropapilloma tumors share genomic drivers and therapeutic vulnerabilities with human cancers
DJ Duffy, C Schnitzler, L Karpinski, R Thomas, J Whilde, C Eastman, ...
Communications Biology 1 (1), 1-13, 2018
372018
Integrative omics reveals MYCN as a global suppressor of cellular signalling and enables network-based therapeutic target discovery in neuroblastoma
DJ Duffy, A Krstic, M Halasz, T Schwarzl, D Fey, K Iljin, JP Mehta, K Killick, ...
Oncotarget 6 (41), 43182, 2015
342015
A brain-derived neurotrophic factor mimetic is sufficient to restore cone photoreceptor visual function in an inherited blindness model
C Daly, L Shine, T Heffernan, S Deeti, AL Reynolds, JJ O’Connor, ...
Scientific reports 7 (1), 1-18, 2017
322017
Precision wildlife medicine: applications of the human‐centred precision medicine revolution to species conservation
J Whilde, MQ Martindale, DJ Duffy
Global Change Biology 23 (5), 1792-1805, 2017
322017
Retinoic acid and TGF-β signalling cooperate to overcome MYCN-induced retinoid resistance
DJ Duffy, A Krstic, M Halasz, T Schwarzl, A Konietzny, K Iljin, DG Higgins, ...
Genome medicine 9 (1), 1-22, 2017
302017
A heat shock protein and Wnt signaling crosstalk during axial patterning and stem cell proliferation
DJ Duffy, RC Millane, U Frank
Developmental biology 362 (2), 271-281, 2012
302012
Wnt signalling is a bi-directional vulnerability of cancer cells
DJ Duffy, A Krstic, T Schwarzl, M Halasz, K Iljin, D Fey, B Haley, J Whilde, ...
Oncotarget 7 (37), 60310, 2016
282016
p19-INK4d inhibits neuroblastoma cell growth, induces differentiation and is hypermethylated and downregulated in MYCN-amplified neuroblastomas
D Dreidax, S Bannert, KO Henrich, C Schroeder, S Bender, CC Oakes, ...
Human molecular genetics 23 (25), 6826-6837, 2014
242014
Advances in dynamic modeling of colorectal cancer signaling-network regions, a path toward targeted therapies
L Tortolina, DJ Duffy, M Maffei, N Castagnino, AM Carmody, W Kolch, ...
Oncotarget 6 (7), 5041, 2015
222015
Plastic ingestion in post-hatchling sea turtles: assessing a major threat in Florida near shore waters
CB Eastman, JA Farrell, L Whitmore, DR Rollinson Ramia, RS Thomas, ...
Frontiers in Marine Science, 693, 2020
212020
Molecular characterization of a marine turtle tumor epizootic, profiling external, internal and postsurgical regrowth tumors
K Yetsko, JA Farrell, NB Blackburn, L Whitmore, MR Stammnitz, J Whilde, ...
Communications biology 4 (1), 1-16, 2021
192021
Measuring transcription rate changes via time-course 4-thiouridine pulse-labelling improves transcriptional target identification
T Schwarzl, DG Higgins, W Kolch, DJ Duffy
Journal of molecular biology 427 (21), 3368-3374, 2015
142015
Modulation of COUP-TF expression in a cnidarian by ectopic Wnt signalling and allorecognition
DJ Duffy, U Frank
PloS one 6 (4), e19443, 2011
142011
Mutational, transcriptional and viral shedding dynamics of the marine turtle fibropapillomatosis tumor epizootic
K Yetsko, J Farrell, MR Stammnitz, L Whitmore, J Whilde, CB Eastman, ...
Biorxiv, 2020
132020
Modulation of Wnt signaling: A route to speciation?
DJ Duffy
Communicative & integrative biology 4 (1), 59-61, 2011
132011
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Articles 1–20