| Raf-1 activates MAP kinase-kinase JM Kyriakis, H App, X Zhang, P Banerjee, DL Brautigan, UR Rapp, ... Nature 358 (6385), 417-421, 1992 | 1712 | 1992 |
| SU5416 is a potent and selective inhibitor of the vascular endothelial growth factor receptor (Flk-1/KDR) that inhibits tyrosine kinase catalysis, tumor vascularization, and … TAT Fong, LK Shawver, L Sun, C Tang, H App, TJ Powell, YH Kim, ... Cancer research 59 (1), 99-106, 1999 | 1327 | 1999 |
| Synthesis and biological evaluations of 3-substituted indolin-2-ones: a novel class of tyrosine kinase inhibitors that exhibit selectivity toward particular receptor tyrosine … L Sun, N Tran, F Tang, H App, P Hirth, G McMahon, C Tang Journal of medicinal chemistry 41 (14), 2588-2603, 1998 | 632 | 1998 |
| Flk-1 as a target for tumor growth inhibition LM Strawn, G McMahon, H App, R Schreck, WR Kuchler, MP Longhi, ... Cancer Research 56 (15), 3540-3545, 1996 | 450 | 1996 |
| Tyrphostins. 5. Potent inhibitors of platelet-derived growth factor receptor tyrosine kinase: structure− activity relationships in quinoxalines, quinolines, and indole tyrphostins A Gazit, H App, G McMahon, J Chen, A Levitzki, FD Bohmer Journal of medicinal chemistry 39 (11), 2170-2177, 1996 | 324 | 1996 |
| Sputum rheology changes in cystic fibrosis lung disease following two different types of physiotherapy: flutter vs autogenic drainage EM App, R Kieselmann, D Reinhardt, H Lindemann, B Dasgupta, M King, ... Chest 114 (1), 171-177, 1998 | 261 | 1998 |
| Acute and long-term amiloride inhalation in cystic fibrosis lung disease EM App, M King, R Helfesrieder, D Kohler, H Matthys Am Rev Respir Dis 141, 605-612, 1990 | 229 | 1990 |
| Interleukin 2 induces tyrosine phosphorylation and activation of p72-74 Raf-1 kinase in a T-cell line. B Turner, U Rapp, H App, M Greene, K Dobashi, J Reed Proceedings of the National Academy of Sciences 88 (4), 1227-1231, 1991 | 224 | 1991 |
| Colony stimulating factor‐1 (CSF‐1) stimulates temperature dependent phosphorylation and activation of the RAF‐1 proto‐oncogene product. M Baccarini, DM Sabatini, H App, UR Rapp, ER Stanley The EMBO journal 9 (11), 3649-3657, 1990 | 159 | 1990 |
| Ras controls coupling of growth factor receptors and protein kinase C in the membrane to Raf-1 and B-Raf protein serine kinases in the cytosol J Troppmair, JT Bruder, H App, H Cai, L Liptak, J Szeberenyi, GM Cooper, ... Oncogene 7 (9), 1867-1873, 1992 | 158 | 1992 |
| Nacystelyn, a novel lysine salt of N-acetylcysteine, to augment cellular antioxidant defence in vitro A Gillissen, M Jaworska, M Orth, M Coffiner, P Maes, EM App, AM Cantin, ... Respiratory medicine 91 (3), 159-168, 1997 | 155 | 1997 |
| Leitlinie zur Diagnostik und Therapie von Patienten mit chronisch obstruktiver Bronchitis und Lungenemphysem (COPD) C Vogelmeier, R Buhl, O Burghuber, CP Criée, S Ewig, J Godnic-Cvar, ... Pneumologie 72 (04), 253-308, 2018 | 152 | 2018 |
| Epidermal growth factor (EGF) stimulates association and kinase activity of Raf-1 with the EGF receptor H App, R Hazan, A Zilberstein, A Ullrich, J Schlessinger, U Rapp Molecular and cellular biology, 1991 | 152 | 1991 |
| Insulin activates the Raf-1 protein kinase. PJ Blackshear, DM Haupt, H App, UR Rapp Journal of Biological Chemistry 265 (21), 12131-12134, 1990 | 140 | 1990 |
| Amiloride inhalation therapy in cystic fibrosis: influence on ion content, hydration, and rheology of sputum RP Tomkiewicz, EM App, JG Zayas, O Ramirez, N Church, RC Boucher, ... American Review of Respiratory Disease, 2012 | 123 | 2012 |
| Heterotrophic 15N2 Fixation and Distribution of Newly Fixed Nitrogen in a Rice-Flooded Soil System DL Eskew, ARJ Eaglesham, AA App Plant physiology 68 (1), 48-52, 1981 | 111 | 1981 |
| Screening assays for compounds KP Hirth, H App, J Tsai US Patent 5,763,198, 1998 | 109 | 1998 |
| Quinazoline compounds and compositions thereof for the treatment of disease H App, GM McMahon, PC Tang, A Gazit, A Levitzki US Patent 5,792,771, 1998 | 107 | 1998 |
| Tyrphostins IV—highly potent inhibitors of EGF receptor kinase. Structure-activity relationship study of 4-anilidoquinazolines A Gazit, J Chen, H App, G McMahon, P Hirth, I Chen, A Levitzki Bioorganic & Medicinal Chemistry 4 (8), 1203-1207, 1996 | 98 | 1996 |
| Nonsymbiotic nitrogen fixation associated with the rice plant in flooded soils AA App, I Watanabe, M Alexander, W Ventura, C Daez, T Santiago, ... Soil Science 130 (5), 283-289, 1980 | 94 | 1980 |
