| The macrophage-inducible C-type lectin, mincle, is an essential component of the innate immune response to Candida albicans CA Wells, JA Salvage-Jones, X Li, K Hitchens, S Butcher, RZ Murray, ... The Journal of Immunology 180 (11), 7404-7413, 2008 | 479 | 2008 |
| Structure of a calpain Ca2+-binding domain reveals a novel EF-hand and Ca2+-induced conformational changes H Blanchard, P Grochulski, Y Li, JSC Arthur, PL Davies, JS Elce, M Cygler Nature structural biology 4 (7), 532-538, 1997 | 277 | 1997 |
| The three-dimensional structure of caspase-8: an initiator enzyme in apoptosis H Blanchard, L Kodandapani, PRE Mittl, S Di Marco, JF Krebs, JC Wu, ... Structure 7 (9), 1125-1133, 1999 | 241 | 1999 |
| Sialic acid dependence in rotavirus host cell invasion T Haselhorst, FE Fleming, JC Dyason, RD Hartnell, X Yu, G Holloway, ... Nature chemical biology 5 (2), 91-93, 2009 | 198 | 2009 |
| Galectin‐3‐binding glycomimetics that strongly reduce bleomycin‐induced lung fibrosis and modulate intracellular glycan recognition T Delaine, P Collins, A MacKinnon, G Sharma, J Stegmayr, VK Rajput, ... ChemBioChem 17 (18), 1759-1770, 2016 | 178 | 2016 |
| Structural and kinetic characterization of a β-lactamase-inhibitor protein NCJ Strynadka, SE Jensen, K Johns, H Blanchard, M Page, A Matagne, ... Nature 368 (6472), 657-660, 1994 | 165 | 1994 |
| Galectin-1 as a potent target for cancer therapy: role in the tumor microenvironment K Ito, K Stannard, E Gabutero, AM Clark, SY Neo, S Onturk, H Blanchard, ... Cancer and Metastasis Reviews 31, 763-778, 2012 | 154 | 2012 |
| Human and mouse macrophage-inducible C-type lectin (Mincle) bind Candida albicans A Bugarcic, K Hitchens, AG Beckhouse, CA Wells, RB Ashman, ... Glycobiology 18 (9), 679-685, 2008 | 129 | 2008 |
| Galectin-3 inhibitors: a patent review (2008–present) H Blanchard, X Yu, PM Collins, K Bum-Erdene Expert opinion on therapeutic patents 24 (10), 1053-1065, 2014 | 114 | 2014 |
| Thiodigalactoside inhibits murine cancers by concurrently blocking effects of galectin-1 on immune dysregulation, angiogenesis and protection against oxidative stress K Ito, SA Scott, S Cutler, LF Dong, J Neuzil, H Blanchard, SJ Ralph Angiogenesis 14, 293-307, 2011 | 112 | 2011 |
| Galectin inhibitory disaccharides promote tumour immunity in a breast cancer model KA Stannard, PM Collins, K Ito, EM Sullivan, SA Scott, E Gabutero, ... Cancer letters 299 (2), 95-110, 2010 | 110 | 2010 |
| Insight into host cell carbohydrate-recognition by human and porcine rotavirus from crystal structures of the virion spike associated carbohydrate-binding domain (VP8*) H Blanchard, X Yu, BS Coulson, M von Itzstein Journal of molecular biology 367 (4), 1215-1226, 2007 | 106 | 2007 |
| Galectin-1 inhibitors and their potential therapeutic applications: a patent review H Blanchard, K Bum-Erdene, MH Bohari, X Yu Expert Opinion on Therapeutic Patents 26 (5), 537-554, 2016 | 92 | 2016 |
| Caspase-8 specificity probed at subsite S4: crystal structure of the caspase-8-Z-DEVD-cho complex H Blanchard, M Donepudi, M Tschopp, L Kodandapani, JC Wu, ... Journal of molecular biology 302 (1), 9-16, 2000 | 92 | 2000 |
| Galectin-3 interactions with glycosphingolipids PM Collins, K Bum-Erdene, X Yu, H Blanchard Journal of molecular biology 426 (7), 1439-1451, 2014 | 80 | 2014 |
| Slow diffusion of lactose out of galectin-3 crystals monitored by X-ray crystallography: possible implications for ligand-exchange protocols PM Collins, KIPJ Hidari, H Blanchard Acta Crystallographica Section D: Biological Crystallography 63 (3), 415-419, 2007 | 76 | 2007 |
| A selective galactose–coumarin-derived galectin-3 inhibitor demonstrates involvement of galectin-3-glycan interactions in a pulmonary fibrosis model VK Rajput, A MacKinnon, S Mandal, P Collins, H Blanchard, H Leffler, ... Journal of medicinal chemistry 59 (17), 8141-8147, 2016 | 74 | 2016 |
| Taloside Inhibitors of Galectin‐1 and Galectin‐3 PM Collins, CT Öberg, H Leffler, UJ Nilsson, H Blanchard Chemical biology & drug design 79 (3), 339-346, 2012 | 74 | 2012 |
| Relative Roles of GM1 Ganglioside, N-Acylneuraminic Acids, and α2β1 Integrin in Mediating Rotavirus Infection FE Fleming, R Böhm, VT Dang, G Holloway, T Haselhorst, PD Madge, ... Journal of virology 88 (8), 4558-4571, 2014 | 70 | 2014 |
| CuAAC synthesis of resorcin [4] arene-based glycoclusters as multivalent ligands of lectins ZH Soomro, S Cecioni, H Blanchard, JP Praly, A Imberty, S Vidal, ... Organic & Biomolecular Chemistry 9 (19), 6587-6597, 2011 | 65 | 2011 |
